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UniProtKB/Swiss-Prot entry Q9Z9F4


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name LON_CHLPN
Primary accession number Q9Z9F4
Secondary accession number Q9JQ69
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on May 1, 1999 (Sequence version 1)
Annotations were last modified on    December 16, 2008 (Entry version 63)
Name and origin of the protein
Protein name ATP-dependent protease La
Synonym EC 3.4.21.53
Gene name
Name: lon
OrderedLocusNames: CPn_0027, CP_0749, CpB0031
From
Chlamydia pneumoniae (Chlamydophila pneumoniae) [TaxID: 83558] [HAMAP proteome]
Taxonomy Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae; Chlamydophila.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CWL029;
DOI=10.1038/7716; PubMed=10192388 [NCBI, ExPASy, EBI, Israel, Japan]
Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W., Olinger L., Grimwood J., Davis R.W., Stephens R.S.;
"Comparative genomes of Chlamydia pneumoniae and C. trachomatis.";
Nat. Genet. 21:385-389(1999).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AR39;
DOI=10.1093/nar/28.6.1397; PubMed=10684935 [NCBI, ExPASy, EBI, Israel, Japan]
Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L., Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M.;
"Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39.";
Nucleic Acids Res. 28:1397-1406(2000).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=J138;
DOI=10.1093/nar/28.12.2311; PubMed=10871362 [NCBI, ExPASy, EBI, Israel, Japan]
Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.;
"Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA.";
Nucleic Acids Res. 28:2311-2314(2000).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=TW-183;
Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.;
"The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis.";
Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE001363; AAD18180.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE002161; AAF38554.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BA000008; BAA98239.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE017157; AAP97964.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR B72128; B72128.
E86494; E86494.
RefSeq NP_224235.1; -.
NP_300088.1; -.
NP_445291.1; -.
NP_876307.1; -.
3D structure databases
ModBase Q9Z9F4.
Protein family/group databases
MEROPS S16.002; -.
Enzyme and pathway databases
BioCyc CPNE115711:CP_0749-MON; -.
CPNE115713:CPN0027-MON; -.
CPNE138677:CPJ0027-MON; -.
CPNE182082:CPB0031-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from InterPro).
GO:0004176; Molecular function: ATP-dependent peptidase activity (inferred from electronic annotation from InterPro).
GO:0017111; Molecular function: nucleoside-triphosphatase activity (inferred from electronic annotation from InterPro).
GO:0004252; Molecular function: serine-type endopeptidase activity (inferred from electronic annotation from InterPro).
GO:0006510; Biological process: ATP-dependent proteolysis (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR003593; AAA+_ATPase_core.
IPR003959; AAA_ATPase_core.
IPR001270; Chaprnin_clpA/B.
IPR008269; Pept_S16_C.
IPR004815; Pept_S16_lon.
IPR003111; Pept_S16_N.
IPR001984; Peptidase_S16.
IPR008268; Peptidase_S16_AS.
Graphical view of domain structure.
Pfam PF00004; AAA; 1.
PF02190; LON; 1.
PF05362; Lon_C; 1.
Pfam graphical view of domain structure.
PRINTS PR00300; CLPPROTEASEA.
PR00830; ENDOLAPTASE.
SMART SM00382; AAA; 1.
SM00464; LON; 1.
SMART graphical view of domain structure.
TIGRFAMs TIGR00763; lon; 1.
PROSITE PS01046; LON_SER; 1.
Genome annotation databases
GeneID 1466714; -.
894928; -.
918819; -.
963156; -.
GenomeReviews AE001363_GR; CPn_0027.
AE002161_GR; CP_0749.
AE009440_GR; CpB0031.
BA000008_GR; lon.
KEGG cpa:CP0749; -.
cpn:CPn0027; -.
cpt:CpB0031; -.
TIGR CP_0749; -.
Phylogenomic databases
HOGENOM Q9Z9F4; -.
Other
ProtoNet Q9Z9F4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Complete proteome; Cytoplasm; Hydrolase; Nucleotide-binding; Protease; Serine protease.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   819  819     ATP-dependent protease La. PRO_0000076131
DOMAIN   42   238  197     Lon. 
NP_BIND   393   400  8     ATP (Potential). 
ACT_SITE   723   723        By similarity. 
ACT_SITE   766   766        By similarity. 
Sequence information
Length: 819 AA [This is the length of the unprocessed precursor] Molecular weight: 92276 Da [This is the MW of the unprocessed precursor] CRC64: 788BCB2A0D294E6A [This is a checksum on the sequence]
        10         20         30         40         50         60 
MDSTTNSDSP ILDPNPEDVE KLLDESEEES EDQSTERLLP SELFILPLNK RPFFPGMAAP 

        70         80         90        100        110        120 
ILIESGPYYE VLKVLAKSSQ KYIGLVLTKK ENADILKVSF NQLHKTGVAA RILRIMPIEG 

       130        140        150        160        170        180 
GSAQVLLSIE ERIRIIEPIK DKYLKARVSY HADNKELTEE LKAYSISIVS VIKDLLKLNP 

       190        200        210        220        230        240 
LFKEELQIFL GHSDFTEPGK LADFSVALTT ATREELQEVL ETTNMHDRID KALILLKKEL 

       250        260        270        280        290        300 
DLSRLQSSIN QKIEATITKS QKEFFLKEQL KTIKKELGLE KEDRAIDIEK FSERLRKRHV 

       310        320        330        340        350        360 
PDYAMEVIQD EIEKLQTLET SSAEYTVCRN YLDWLTIIPW GIQSKEYHDL KKAEIVLNKD 

       370        380        390        400        410        420 
HYGLDEIKQR ILELISVGKL SKGLKGSIIC LVGPPGVGKT SIGRSIAKVL HRKFFRFSVG 

       430        440        450        460        470        480 
GMRDEAEIKG HRRTYIGAMP GKMVQALKQS QAMNPVIMID EVDKIGASYH GDPASALLEV 

       490        500        510        520        530        540 
LDPEQNKDFL DHYLDVRVDL SNVLFILTAN VLDTIPDPLL DRMEILRLSG YILEEKLQIA 

       550        560        570        580        590        600 
KKYLVPKARK EIGLTASEVN FQPEALKYMI NNYAREAGVR TLNGNIKKVL RKVALKIVQN 

       610        620        630        640        650        660 
QEKPKSKKIT FKISSKNLQT YLGKPIFSSD RFYESTPVGV ATGLAWTSLG GATLYIESVQ 

       670        680        690        700        710        720 
VSSLKTDMHL TGQAGEVMKE SSQIAWTYLH SALHRYAPGY TFFPKSQVHI HIPEGATPKD 

       730        740        750        760        770        780 
GPSAGITMVT SLLSLLLETP VVNNLGMTGE ITLTGRVLGV GGIREKLIAA RRSRLNILIF 

       790        800        810 
PEDNRRDYEE LPAYLKTGLK IHFVSHYDDV LKVAFPKLK 

Q9Z9F4 in FASTA format

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