ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q9HSS7

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name G3P_HALSA
Primary accession number Q9HSS7
Secondary accession numbers None
Integrated into Swiss-Prot on May 27, 2002
Sequence was last modified on March 1, 2001 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 54)
Name and origin of the protein
Protein name Glyceraldehyde-3-phosphate dehydrogenase
Synonyms GAPDH
EC 1.2.1.59
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase
Gene name
Name: gap
Synonyms: gapB
OrderedLocusNames: VNG_0095G
From
Halobacterium salinarium (Halobacterium halobium) [TaxID: 2242] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; Halobacterium.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
DOI=10.1073/pnas.190337797; PubMed=11016950 [NCBI, ExPASy, EBI, Israel, Japan]
Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D., Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D., Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R., Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P., Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M., Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J., Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L., DasSarma S.;
"Genome sequence of Halobacterium species NRC-1.";
Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE004437; AAG18725.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A84170; A84170.
RefSeq NP_279245.1; -.
3D structure databases
HSSP P10618; 1CF2. [HSSP ENTRY / PDB]
ModBase Q9HSS7.
Enzyme and pathway databases
BioCyc HSP64091:VNG0095G-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0043891; Molecular function: glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity (inferred from electronic annotation from EC).
GO:0004365; Molecular function: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity (inferred from electronic annotation from HAMAP).
GO:0051287; Molecular function: NAD binding (inferred from electronic annotation from InterPro).
GO:0050661; Molecular function: NADP binding (inferred from electronic annotation from InterPro).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_00559; -; 1.
PBIL [Tree]
InterPro IPR000173; GlycerAld_3-P_DHase.
IPR006436; Glyceraldehyde-3-P_DHase_2_arc.
Graphical view of domain structure.
Pfam PF02800; Gp_dh_C; 1.
PF00044; Gp_dh_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000149; GAP_DH; 1.
ProDom PD007761; GAPDH_like; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01546; GAPDH-II_archae; 1.
PROSITE PS00071; GAPDH; 1.
ProtoNet Q9HSS7.
Genome annotation databases
GeneID 1447029; -.
GenomeReviews AE004437_GR; VNG_0095G.
KEGG hal:VNG0095G; -.
NMPDR fig|64091.1.peg.257; -.
Phylogenomic databases
HOGENOM Q9HSS7; -.
Genome annotation databases
CMR Q9HSS7; VNG_0095G.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Glycolysis; NAD; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   335  335     Glyceraldehyde-3-phosphate dehydrogenase. PRO_0000145717
NP_BIND   11    12  2     NAD (By similarity). 
REGION   139   141  3     Glyceraldehyde 3-phosphate binding (By similarity). 
REGION   194   195  2     Glyceraldehyde 3-phosphate binding (By similarity). 
ACT_SITE   140   140        Nucleophile (By similarity). 
BINDING   110   110        NAD; via amide nitrogen (By similarity). 
BINDING   168   168        NAD (By similarity). 
BINDING   301   301        NAD; via carbonyl oxygen (By similarity). 
Sequence information
Length: 335 AA [This is the length of the unprocessed precursor] Molecular weight: 35683 Da [This is the MW of the unprocessed precursor] CRC64: CA10FD928E368CB1 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MIRVGINGYG TIGKRVADAV AAQPDMTVAG VAKTSPNFEA TQARKRGFDL YTAVEDRADQ 

        70         80         90        100        110        120 
FPAAGIETAG PVDDLIADSD VVVDATPSGV GAENRSRYAA HDTPAIYQGG EDASVADVSF 

       130        140        150        160        170        180 
NARANFEAAA DADHVRVVSC NTTGLSRLLA PLREQYGIEK VRATLVRRGG DPGQTDRGPI 

       190        200        210        220        230        240 
NDILPDPITI PSHHGPDVNT IFPDLDIDTL GMKVPATLMH MHSINVTLER DPDAADVRDV 

       250        260        270        280        290        300 
LAGQSRIMLL DDDLGIDGTG PLKEYAQDMG RPRGDLWENC LWGESVTMDG RDFYCFQAIH 

       310        320        330 
QESDVVPENV DAVRAIAGDA DAAESIATTN DALGI
Q9HSS7 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by ca flag CBR Canada Mirror sites: Australia Brazil China Korea Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!