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UniProtKB/Swiss-Prot entry Q8EAC7

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NRFA_SHEON
Primary accession number Q8EAC7
Secondary accession numbers None
Integrated into Swiss-Prot on December 12, 2006
Sequence was last modified on March 1, 2003 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 45)
Name and origin of the protein
Protein name Cytochrome c-552 [Precursor]
Synonyms EC 1.7.2.2
Ammonia-forming cytochrome c nitrite reductase
Cytochrome c nitrite reductase
Gene name
Name: nrfA
OrderedLocusNames: SO_3980
From
Shewanella oneidensis [TaxID: 70863] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales; Shewanellaceae; Shewanella.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=MR-1;
DOI=10.1038/nbt749; PubMed=12368813 [NCBI, ExPASy, EBI, Israel, Japan]
Heidelberg J.F., Paulsen I.T., Nelson K.E., Gaidos E.J., Nelson W.C., Read T.D., Eisen J.A., Seshadri R., Ward N.L., Methe B.A., Clayton R.A., Meyer T., Tsapin A., Scott J., Beanan M.J., Brinkac L.M., Daugherty S.C., DeBoy R.T., Dodson R.J., Durkin A.S., Haft D.H., Kolonay J.F., Madupu R., Peterson J.D., Umayam L.A., White O., Wolf A.M., Vamathevan J.J., Weidman J.F., Impraim M., Lee K., Berry K.J., Lee C., Mueller J., Khouri H.M., Gill J., Utterback T.R., McDonald L.A., Feldblyum T.V., Smith H.O., Venter J.C., Nealson K.H., Fraser C.M.;
"Genome sequence of the dissimilatory metal ion-reducing bacterium Shewanella oneidensis.";
Nat. Biotechnol. 20:1118-1123(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE014299; AAN56954.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_719510.1; -.
3D structure databases
HSSP P32050; 1GU6. [HSSP ENTRY / PDB]
ModBase Q8EAC7.
Enzyme and pathway databases
BioCyc SONE211586:SO_3980-MON; -.
Ontologies
GO
GO:0042597; Cellular component: periplasmic space (inferred from electronic annotation from HAMAP).
GO:0005509; Molecular function: calcium ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0042279; Molecular function: nitrite reductase (cytochrome, ammonia-forming) activity (inferred from electronic annotation from HAMAP).
GO:0022900; Biological process: electron transport chain (inferred from electronic annotation from UniProtKB-KW).
GO:0006807; Biological process: nitrogen compound metabolic process (inferred from electronic annotation from HAMAP).
GO:0006810; Biological process: transport (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_01182; -; 1.
PBIL [Tree]
InterPro IPR003321; Cyt_c552.
IPR017570; Cytc_552_NO2Rdtase_formate-dep.
IPR011031; Multihaem_cyt.
Graphical view of domain structure.
Pfam PF02335; Cytochrom_C552; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000243; Cyt_c552; 1.
PROSITE PS51008; MULTIHEME_CYTC; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q8EAC7.
ProtoNet Q8EAC7.
Genome annotation databases
GeneID 1171612; -.
GenomeReviews AE014299_GR; SO_3980.
KEGG son:SO_3980; -.
NMPDR fig|211586.1.peg.3613; -.
TIGR SO_3980; -.
Phylogenomic databases
HOGENOM Q8EAC7; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Calcium; Complete proteome; Electron transport; Heme; Iron; Metal-binding; Oxidoreductase; Periplasm; Signal; Transport.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
SIGNAL   1    27  27     Potential. 
CHAIN   28   467  440     Cytochrome c-552. PRO_0000268975
METAL   87    87        Iron (heme 3 axial ligand) (By similarity). 
METAL   119   119        Iron (heme 1 axial ligand) (By similarity). 
METAL   157   157        Iron (heme 2 axial ligand) (By similarity). 
METAL   199   199        Iron (heme 3 axial ligand) (By similarity). 
METAL   201   201        Calcium (By similarity). 
METAL   202   202        Calcium; via carbonyl oxygen (By similarity). 
METAL   250   250        Calcium; via carbonyl oxygen (By similarity). 
METAL   252   252        Calcium (By similarity). 
METAL   264   264        Iron (heme 5 axial ligand) (By similarity). 
METAL   275   275        Iron (heme 4 axial ligand) (By similarity). 
METAL   290   290        Iron (heme 2 axial ligand) (By similarity). 
METAL   307   307        Iron (heme 5 axial ligand) (By similarity). 
METAL   382   382        Iron (heme 4 axial ligand) (By similarity). 
BINDING   115   115        Heme 1 (covalent) (By similarity). 
BINDING   118   118        Heme 1 (covalent) (By similarity). 
BINDING   153   153        Heme 2 (covalent) (By similarity). 
BINDING   156   156        Heme 2 (covalent) (By similarity). 
BINDING   195   195        Heme 3 (covalent) (By similarity). 
BINDING   198   198        Heme 3 (covalent) (By similarity). 
BINDING   202   202        Substrate (By similarity). 
BINDING   253   253        Substrate (By similarity). 
BINDING   271   271        Heme 4 (covalent) (By similarity). 
BINDING   274   274        Heme 4 (covalent) (By similarity). 
BINDING   303   303        Heme 5 (covalent) (By similarity). 
BINDING   306   306        Heme 5 (covalent) (By similarity). 
Sequence information
Length: 467 AA [This is the length of the unprocessed precursor] Molecular weight: 52334 Da [This is the MW of the unprocessed precursor] CRC64: 4BC976E90CDC48E0 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MMKKMTGKTF ALSALVAASF MAAGAMASDK TEPRNEVYKD KFKNQYNSWH DTAKSEELVD 

        70         80         90        100        110        120 
ALEQDPNMVI LWAGYAFAKD YKAPRGHMYA VTDVRNTLRT GAPKNAEDGP LPMACWSCKS 

       130        140        150        160        170        180 
PDVPRLIEEQ GEDGYFKGKW AKGGPEVTNT IGCSDCHEKG SPKLRISRPY VDRALDAIGT 

       190        200        210        220        230        240 
PFSKASKQDK ESMVCAQCHV EYYFEKKEDK KGFVKFPWDM GVTVDQMEVY YDGIEFSDWT 

       250        260        270        280        290        300 
HALSKTPMLK AQHPEYETWK MGIHGKNNVS CVDCHMPKVT SPEGKKFTDH KVGNPFDRFE 

       310        320        330        340        350        360 
ETCATCHSQT KEFLVGVTNE RKAKVKEMKL KAEEQLVKAH FEAAKAWELG ATEAEMKPIL 

       370        380        390        400        410        420 
TDIRHAQWRW DLAIASHGVA AHAPEEALRV LGTSVNKAAD ARVKLAQLLA KKGLTDPVAI 

       430        440        450        460 
PDISTKAKAQ AVLGMDMEKM NAEKEAFKKD MLPKWDAEAK KREATYK
Q8EAC7 in FASTA format

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