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UniProtKB/Swiss-Prot entry P60336

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name BETA_STAAM
Primary accession number P60336
Secondary accession number Q99R25
Integrated into Swiss-Prot on February 16, 2004
Sequence was last modified on February 16, 2004 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 33)
Name and origin of the protein
Protein name Choline dehydrogenase
Synonyms CHD
CDH
EC 1.1.99.1
Gene name
Name: betA
OrderedLocusNames: SAV2612
From
Staphylococcus aureus (strain Mu50 / ATCC 700699) [TaxID: 158878] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Staphylococcus.
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1016/S0140-6736(00)04403-2; PubMed=11418146 [NCBI, ExPASy, EBI, Israel, Japan]
Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L., Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M., Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y., Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H., Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K., Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H., Hiramatsu K.;
"Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
Lancet 357:1225-1240(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000017; BAB58774.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_373136.1; -.
3D structure databases
ModBase P60336.
Enzyme and pathway databases
BioCyc SAUR158878:SAV2612-MON; -.
2D gel databases
World-2DPAGE 0002:P60336; -.
Ontologies
GO
GO:0008812; Molecular function: choline dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0050660; Molecular function: FAD binding (inferred from electronic annotation from InterPro).
GO:0006066; Biological process: cellular alcohol metabolic process (inferred from electronic annotation from InterPro).
GO:0019285; Biological process: glycine betaine biosynthetic process from choline (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_00750; -; 1.
PBIL [Tree]
InterPro IPR011533; Choline_dehydrogenase.
IPR012132; GMC_OxRdtase.
IPR000172; GMC_OxRdtase_N.
IPR007867; GMC_OxRtase_C.
Graphical view of domain structure.
Pfam PF05199; GMC_oxred_C; 1.
PF00732; GMC_oxred_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000137; Alcohol_oxidase; 1.
TIGRFAMs TIGR01810; betA; 1.
PROSITE PS00623; GMC_OXRED_1; 1.
PS00624; GMC_OXRED_2; 1.
ProtoNet P60336.
Genome annotation databases
GeneID 1122637; -.
GenomeReviews BA000017_GR; SAV2612.
KEGG sav:SAV2612; -.
Phylogenomic databases
HOGENOM P60336; -.
Genome annotation databases
CMR P60336; SAV2612.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; FAD; Flavoprotein; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   569  569     Choline dehydrogenase. PRO_0000205596
NP_BIND   9    38  30     FAD (Probable). 
ACT_SITE   475   475        By similarity. 
Sequence information
Length: 569 AA [This is the length of the unprocessed precursor] Molecular weight: 63610 Da [This is the MW of the unprocessed precursor] CRC64: A6E35293AADDDFA6 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSNKNKSYDY VIIGGGSAGS VLGNRLSEDK DKEVLVLEAG RSDYFWDLFI QMPAALMFPS 

        70         80         90        100        110        120 
GNKFYDWIYS TDEEPHMGGR KVAHARGKVL GGSSSINGMI YQRGNPMDYE GWAEPEGMET 

       130        140        150        160        170        180 
WDFAHCLPYF KKLEKTYGAA PYDKFRGHDG PIKLKRGPAT NPLFQSFFDA GVEAGYHKTP 

       190        200        210        220        230        240 
DVNGFRQEGF GPFDSQVHRG RRMSASRAYL HPAMKRKNLT VETRAFVTEI HYEGRRATGV 

       250        260        270        280        290        300 
TYKKNGKLHT IDANEVILSG GAFNTPQLLQ LSGIGDSEFL KSKGIEPRVH LPGVGENFED 

       310        320        330        340        350        360 
HLEVYIQHKC KEPVSLQPSL DIKRMPFIGL QWIFTRTGAA ASNHFEGGGF VRSNNEVDYP 

       370        380        390        400        410        420 
NLMFHFLPIA VRYDGQKAAV AHGYQVHVGP MYSNSRGSLK IKSKDPFEKP SIRFNYLSTE 

       430        440        450        460        470        480 
EDKKEWVEAI RVARNILSQK AMDPFNGGEI SPGPEVQTDE EILDWVRRDG ETALHPSCSA 

       490        500        510        520        530        540 
KMGPASDPMA VVDPLTMKVH GMENLRVVDA SAMPRTTNGN IHAPVLMLAE KAADIIRGRK 

       550        560 
PLEPQYIDYY KHGVHDENEG AIEVKPYAK
P60336 in FASTA format

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