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UniProtKB/Swiss-Prot entry P56891


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CYSH_RHIME
Primary accession number P56891
Secondary accession numbers None
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on May 30, 2000 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 56)
Name and origin of the protein
Protein name Phosphoadenosine phosphosulfate reductase
Synonyms EC 1.8.4.8
PAPS reductase, thioredoxin dependent
PAdoPS reductase
3'-phosphoadenylylsulfate reductase
PAPS sulfotransferase
Gene name
Name: cysH
OrderedLocusNames: R00944
ORFNames: SMc00092
From
Rhizobium meliloti (Sinorhizobium meliloti) [TaxID: 382] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=1021;
PubMed=10464198 [NCBI, ExPASy, EBI, Israel, Japan]
Abola A.P., Willits M.G., Wang R.C., Long S.R.;
"Reduction of adenosine-5'-phosphosulfate instead of 3'-phosphoadenosine-5'-phosphosulfate in cysteine biosynthesis by Rhizobium meliloti and other members of the family Rhizobiaceae.";
J. Bacteriol. 181:5280-5287(1999).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=1021;
DOI=10.1073/pnas.161294398; PubMed=11481430 [NCBI, ExPASy, EBI, Israel, Japan]
Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J., Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S., Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T., Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C., Thebault P., Vandenbol M., Weidner S., Galibert F.;
"Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021.";
Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF158023; AAD55759.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AL591688; CAC45516.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_385050.1; -.
3D structure databases
HSSP P17854; 1SUR. [HSSP ENTRY / PDB]
ModBase P56891.
Enzyme and pathway databases
BioCyc SMEL266834:SMC00092-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004604; Molecular function: phosphoadenylyl-sulfate reductase (thioredoxin) activity (inferred from electronic annotation from HAMAP).
GO:0016740; Molecular function: transferase activity (inferred from electronic annotation from InterPro).
GO:0019344; Biological process: cysteine biosynthetic process (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0019379; Biological process: sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00063; -; 1.
PBIL [Tree]
InterPro IPR011798; APS_reductase.
IPR002500; PAPS_reduct.
IPR014729; Rossmann-like_a/b/a_fold.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1.
Pfam PF01507; PAPS_reduct; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR02055; APS_reductase; 1.
ProtoNet P56891.
Genome annotation databases
GeneID 1232587; -.
GenomeReviews AL591688_GR; R00944.
KEGG sme:SMc00092; -.
NMPDR fig|266834.1.peg.2238; -.
Phylogenomic databases
HOGENOM P56891; -.
Genome annotation databases
CMR P56891; R00944.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   265  265     Phosphoadenosine phosphosulfate reductase. PRO_0000100640
Sequence information
Length: 265 AA [This is the length of the unprocessed precursor] Molecular weight: 28767 Da [This is the MW of the unprocessed precursor] CRC64: 284F43A6EDC6FE15 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTTQSLKAEA VALEADVMAL DAEAKALNDK LESLDLAGRL ALIAGLEGRA VFTTSLGIED 

        70         80         90        100        110        120 
QVITAAIGSN RLDIEVATLK TGRLFNETVA LIDQTEETYD ILIKRYYPEK ADIDAYVAQY 

       130        140        150        160        170        180 
GMNGFYESVE ARHACCGVRK LKPLARALDG ASYWITGLRR GQSGNRATTP FAEADVERGL 

       190        200        210        220        230        240 
IKINPLADWG IETIQAHVAA EGIPVNPLHS RGYPSIGCEP CTRAIKPGEP ERAGRWWWEN 

       250        260 
DEKRECGLHV PEAASSIIPN ASNAA 

P56891 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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