[1]	PROTEIN SEQUENCE. DOI=10.1007/BF01024941; PubMed=2544196 [NCBI, ExPASy, EBI, Israel, Japan] Chin C.C.Q., Niehaus W.G., Wold F.; "Amino acid sequence of cytochrome c from Aspergillus niger."; J. Protein Chem. 8:165-171(1989).

Comments

FUNCTION: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
SUBCELLULAR LOCATION: Mitochondrion matrix.
PTM: Binds 1 heme group per subunit.
SIMILARITY: Belongs to the cytochrome c family.
WEB RESOURCE: Name=Protein Spotlight; Note=Life shuttle - Issue 76 of November 2006; URL="http://www.expasy.org/spotlight/back_issues/sptlt076.shtml";.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

PIR

A61490; A61490.

3D structure databases

HSSP

P00044; 1CRH. [HSSP ENTRY / PDB]

SMR

P56205; 6-109.

ModBase

P56205.

Ontologies

GO:0005759;	Cellular component: mitochondrial matrix (inferred from electronic annotation from UniProtKB-SubCell).
QuickGo view.

Family and domain databases

InterPro

IPR009056; Cyt_c_monohaem.
IPR003088; Cyt_CI.
IPR002327; Cyt_CIAB.
Graphical view of domain structure.

Gene3D

G3DSA:1.10.760.10; Cytochrome_c_R; 1.

PANTHER

PTHR11961; Cyt_CIAB; 1.

Pfam

PF00034; Cytochrom_C; 1.
Pfam graphical view of domain structure.

PRINTS

PR00604; CYTCHRMECIAB.

ProDom

PD000375; Cyt_CIAB; 1.
[Domain structure / List of seq. sharing at least 1 domain]

PROSITE

PS51007; CYTC; 1.
PROSITE graphical view of domain structure (profiles).

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Direct protein sequencing; Electron transport; Heme; Iron; Metal-binding; Methylation; Mitochondrion; Respiratory chain; Transport.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 111`	`111`	`Cytochrome c.`	`PRO_0000108317`
`METAL`	`26 26`		`Iron (heme axial ligand).`
`METAL`	`88 88`		`Iron (heme axial ligand) (By similarity).`
`BINDING`	`22 22`		`Heme (covalent).`
`BINDING`	`25 25`		`Heme (covalent).`
`MOD_RES`	`80 80`		`N6,N6,N6-trimethyllysine (By similarity).`

Sequence information

Length: 111 AA [This is the length of the unprocessed precursor]

Molecular weight: 11954 Da [This is the MW of the unprocessed precursor]

CRC64: 1F49BA817E205EB1 [This is a checksum on the sequence]

        10         20         30         40         50         60 
GKDASFAPGD SAKGAKLFQT RCAQCHTVEA GGPHKVGPNL HGLFGRKTGQ SEGYAYTDAN 

        70         80         90        100        110 
KQAGVTWDEN TLFSYLENPK KFIPGTKMAF GGLKKGKERN DLITYLKEST A

P56205 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools