NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 2-35.
STRAIN=FR1;
DOI=10.1007/BF00262431; PubMed=2176269 [NCBI, ExPASy, EBI, Israel, Japan]
Majewski C., Trebst A.;
"The pet genes of Rhodospirillum rubrum: cloning and sequencing of the genes for the cytochrome bc1-complex.";
Mol. Gen. Genet. 224:373-382(1990).

Comments

FUNCTION: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
CATALYTIC ACTIVITY: QH₂ + 2 ferricytochrome c = Q + 2 ferrocytochrome c + 2 H⁺.
COFACTOR: Binds 1 2Fe-2S cluster per subunit (By similarity).
SUBUNIT: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.
SUBCELLULAR LOCATION: Cell inner membrane; Single-pass membrane protein.
MISCELLANEOUS: The Rieske protein is a high potential 2Fe-2S protein.
SIMILARITY: Contains 1 Rieske domain.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

X55387; CAA39058.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

S12256; RDQFBR.

3D structure databases

HSSP

P13272; 1RIE. [HSSP ENTRY / PDB]

ModBase

P23136.

Ontologies

GO:0016021;	Cellular component: integral to membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0005886;	Cellular component: plasma membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0051537;	Molecular function: 2 iron, 2 sulfur cluster binding (inferred from electronic annotation from InterPro).
GO:0009055;	Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0005506;	Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0008121;	Molecular function: ubiquinol-cytochrome-c reductase activity (inferred from electronic annotation from InterPro).
GO:0022900;	Biological process: electron transport chain (inferred from electronic annotation from UniProtKB-KW).
GO:0006810;	Biological process: transport (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

InterPro

IPR014349; Rieske.
IPR005805; Rieske_C.
IPR006317; Rieske_proteo.
IPR005806; Rieske_reg.
IPR006311; Tat.
Graphical view of domain structure.

Gene3D

G3DSA:2.102.10.10; Rieske_reg; 1.

PANTHER

PTHR10134; Rieske; 1.

Pfam

PF00355; Rieske; 1.
Pfam graphical view of domain structure.

PRINTS

PR00162; RIESKE.

TIGRFAMs

TIGR01416; Rieske_proteo; 1.
TIGR01409; TAT_signal_seq; 1.

PROSITE

PS51296; RIESKE; 1.
PS51318; TAT; 1.
PROSITE graphical view of domain structure (profiles).

ProtoNet

P23136.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

2Fe-2S; Cell inner membrane; Cell membrane; Direct protein sequencing; Electron transport; Iron; Iron-sulfur; Membrane; Metal-binding; Oxidoreductase; Transmembrane; Transport.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`INIT_MET`	`1 1`		`Removed.`
`CHAIN`	`2 183`	`182`	`Ubiquinol-cytochrome c reductase iron-sulfur subunit.`	`PRO_0000127763`
`TRANSMEM`	`21 41`	`21`	`Potential.`
`DOMAIN`	`88 181`	`94`	`Rieske.`
`METAL`	`121 121`		`Iron-sulfur (2Fe-2S) (By similarity).`
`METAL`	`123 123`		`Iron-sulfur (2Fe-2S); via pros nitrogen (By similarity).`
`METAL`	`145 145`		`Iron-sulfur (2Fe-2S) (By similarity).`
`METAL`	`148 148`		`Iron-sulfur (2Fe-2S); via pros nitrogen (By similarity).`
`DISULFID`	`126 147`		`By similarity.`

Sequence information

Length: 183 AA [This is the length of the unprocessed precursor]

Molecular weight: 19513 Da [This is the MW of the unprocessed precursor]

CRC64: 915729F04701D7F9 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MAEAEHTAST PGGESSRRDF LIYGTTAVGA VGVALAVWPF IDFMNPAADT LALASTEVDV 

        70         80         90        100        110        120 
SAIAEGQAIT VTWRGKPVFV RHRTQKEIVV ARAVDPASLR DPQTDEARVQ QAQWLVMVGV 

       130        140        150        160        170        180 
CTHLGCIPLG QKAGDPKGDF DGWFCPCHGS HYDSAGRIRK GPAPLNLPVP PYAFTDDTTV 


LIG

P23136 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools