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UniProtKB/Swiss-Prot entry P17729

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G3P1_TRIKO
Primary accession number P17729
Secondary accession numbers None
Integrated into Swiss-Prot on August 1, 1990
Sequence was last modified on January 23, 2007 (Sequence version 3)
Annotations were last modified on    November 4, 2008 (Entry version 66)
Name and origin of the protein
Protein name Glyceraldehyde-3-phosphate dehydrogenase 1
Synonyms GAPDH1
EC 1.2.1.12
Gene name
Name: gpd1
From
Trichoderma koningii (Hypocrea koningii) [TaxID: 97093] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes; Hypocreomycetidae; Hypocreales; Hypocreaceae; Hypocrea.
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=M3947;
DOI=10.1016/0167-4781(93)90267-H; PubMed=8439569 [NCBI, ExPASy, EBI, Israel, Japan]
Watanabe H., Hasumi K., Fukushima Y., Sakai K., Endo A.;
"Cloning of two isozymes of Trichoderma koningii glyceraldehyde-3-phosphate dehydrogenase with different sensitivity to koningic acid.";
Biochim. Biophys. Acta 1172:43-48(1993).
[2]
 PROTEIN SEQUENCE OF 2-32.
STRAIN=M3947;
PubMed=2226438 [NCBI, ExPASy, EBI, Israel, Japan]
Sakai K., Hasumi K., Endo A.;
"Two glyceraldehyde-3-phosphate dehydrogenase isozymes from the koningic acid (heptelidic acid) producer Trichoderma koningii.";
Eur. J. Biochem. 193:195-202(1990).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
D14519; BAA03392.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S13205; S13205.
3D structure databases
HSSP P56649; 1IHX. [HSSP ENTRY / PDB]
SMR P17729; 4-335.
ModBase P17729.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR000173; GlycerAld_3-P_DHase.
IPR006424; Glyceraldehyde-3-P_DHase_1.
Graphical view of domain structure.
PANTHER PTHR10836; GAP_DH; 1.
Pfam PF02800; Gp_dh_C; 1.
PF00044; Gp_dh_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000149; GAP_DH; 1.
PRINTS PR00078; G3PDHDRGNASE.
TIGRFAMs TIGR01534; GAPDH-I; 1.
PROSITE PS00071; GAPDH; 1.
BLOCKS P17729.
ProtoNet P17729.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cytoplasm; Direct protein sequencing; Glycolysis; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
INIT_MET   1     1        Removed. 
CHAIN   2   336  335     Glyceraldehyde-3-phosphate dehydrogenase 1. PRO_0000145585
NP_BIND   12    13  2     NAD (By similarity). 
REGION   149   151  3     Glyceraldehyde 3-phosphate binding (By similarity). 
REGION   209   210  2     Glyceraldehyde 3-phosphate binding (By similarity). 
ACT_SITE   150   150        Nucleophile (By similarity). 
BINDING   34    34        NAD (By similarity). 
BINDING   79    79        NAD; via carbonyl oxygen (By similarity). 
BINDING   180   180        Glyceraldehyde 3-phosphate (By similarity). 
BINDING   232   232        Glyceraldehyde 3-phosphate (By similarity). 
BINDING   314   314        NAD (By similarity). 
SITE   177   177  1     Activates thiol group during catalysis (By similarity). 
Sequence information
Length: 336 AA [This is the length of the unprocessed precursor] Molecular weight: 36252 Da [This is the MW of the unprocessed precursor] CRC64: FC8C87E617297066 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MVPKVGINGF GRIGRVVLRN ALETGAVEVV ALNDPFIEPH YAEYMFKYDS THGRFKGDIK 

        70         80         90        100        110        120 
VDGKDLVIDG KRIKFYQERD PANIPWKDSG AEYIVESTGV FTTTEKASAH FKGGAKKVII 

       130        140        150        160        170        180 
SAPSADAPMY VMGVNEDTYA GANVISNASC TTNCLAPLAK TLNDKFTIVE GLMTAIHAYT 

       190        200        210        220        230        240 
ASQKTVDGPS SKDWRGGRAA AQNLIPSSTG AAKAVGKVIP ELAGKVTGMS VRVPTVNVSL 

       250        260        270        280        290        300 
VDFTVRFAKD VTYDEVKAAI KEASEGPLKG ILAYTEDDIV STDILTDPHS STFDAKAGIA 

       310        320        330 
LNKNFVKVMS WYDNEYGYSR RVVDLIVYVS KKDAGQ
P17729 in FASTA format

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