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UniProtKB/Swiss-Prot entry O84066


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name 6PGD_CHLTR
Primary accession number O84066
Secondary accession numbers None
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on November 1, 1998 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 52)
Name and origin of the protein
Protein name 6-phosphogluconate dehydrogenase, decarboxylating
Synonym EC 1.1.1.44
Gene name
Name: gnd
OrderedLocusNames: CT_063
From
Chlamydia trachomatis [TaxID: 813] [HAMAP proteome]
Taxonomy Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae; Chlamydia.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=D/UW-3/Cx;
DOI=10.1126/science.282.5389.754; PubMed=9784136 [NCBI, ExPASy, EBI, Israel, Japan]
Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L., Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W.;
"Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis.";
Science 282:754-759(1998).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE001273; AAC67654.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A71561; A71561.
RefSeq NP_219566.1; -.
3D structure databases
HSSP P00349; 2PGD. [HSSP ENTRY / PDB]
ModBase O84066.
Enzyme and pathway databases
BioCyc CTRA315277:CT063-MON; -.
Ontologies
GO
GO:0019521; Biological process: D-gluconate metabolic process (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR006183; 6-phosphogluconate_DHase.
IPR006114; 6PGDH_C.
IPR006113; 6PGDH_decarbox.
IPR006115; 6PGDH_NAD-bd.
IPR006184; 6PGdom_BS.
IPR013328; DHase_multihelical.
IPR012284; Fibritin/6PGD_C-extension.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:1.20.5.320; Fibritin/6PGD_C-extension; 1.
G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.
Pfam PF00393; 6PGD; 1.
PF03446; NAD_binding_2; 1.
Pfam graphical view of domain structure.
PRINTS PR00076; 6PGDHDRGNASE.
TIGRFAMs TIGR00873; gnd; 1.
PROSITE PS00461; 6PGD; 1.
BLOCKS O84066.
ProtoNet O84066.
Genome annotation databases
GeneID 884061; -.
GenomeReviews AE001273_GR; CT_063.
KEGG ctr:CT063; -.
Phylogenomic databases
HOGENOM O84066; -.
Genome annotation databases
CMR O84066; CT_063.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Gluconate utilization; NADP; Oxidoreductase; Pentose shunt.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   480  480     6-phosphogluconate dehydrogenase, decarboxylating. PRO_0000090033
Sequence information
Length: 480 AA [This is the length of the unprocessed precursor] Molecular weight: 52667 Da [This is the MW of the unprocessed precursor] CRC64: E2D9BFE893DCECB2 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAPNTDIGLI GLAVMGKNLV LNMVDHGFSV SVYNRSPAKT EEFLKDHGES GALQGFTTIQ 

        70         80         90        100        110        120 
EFVQSLKRPR KIMIMIKAGA PVDEMIASLL PFLEEGDILI DGGNSYYLDS EQRYVDLKKE 

       130        140        150        160        170        180 
GILFVGMGVS GGEEGARKGP SIMPGGNIDA WPAIAPIFQS IAAQVDGRPC CSWIGTGGAG 

       190        200        210        220        230        240 
HFVKAVHNGI EYGDIQLICE TYEILKTRLN LSLEQIGNIF FEWNQTDLNS YLIGAAAAVL 

       250        260        270        280        290        300 
IAKDENGNAI ASTILDVAGQ KGTGRWVAED AIKAGVPMSL IIESVLARYL STWKEVRTKA 

       310        320        330        340        350        360 
AQEFPGIPLL CQPPQEASAF IEDVREALYA AKIISYAQGF MLLKQVSQDK GWDLNLGELA 

       370        380        390        400        410        420 
LIWRGGCIIQ SAFLDKIHQG FENSPEAHSL ILQDYFKKVL FDSETGFRRA VLHAIGSGVA 

       430        440        450        460        470        480 
IPCLSSALSF YDGYRTVDSS LFLVQGLRDY FGAHGYERRD CPRGEFYHTD WLETKKTFRV 

O84066 in FASTA format

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