NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=CFN 299;
PubMed=9773278 [NCBI, ExPASy, EBI, Israel, Japan]
Laeremans T., Martinez-Romero E., Vanderleyden J.;
"Isolation and sequencing of a second Rhizobium tropici CFN299 genetic locus that contains genes homologous to amino acid sulphate activation genes.";
DNA Seq. 9:65-70(1998).

Comments

FUNCTION: Reduction of activated sulfate into sulfite.
CATALYTIC ACTIVITY: Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin.
PATHWAY: Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3 .
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the PAPS reductase family. CysH subfamily.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AJ001223; CAA04617.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

HSSP

P17854; 1SUR. [HSSP ENTRY / PDB]

ModBase

O33579.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004604;	Molecular function: phosphoadenylyl-sulfate reductase (thioredoxin) activity (inferred from electronic annotation from HAMAP).
GO:0016740;	Molecular function: transferase activity (inferred from electronic annotation from InterPro).
GO:0019344;	Biological process: cysteine biosynthetic process (inferred from electronic annotation from InterPro).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0019379;	Biological process: sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00063; -; 1.
PBIL [Tree]

InterPro

IPR011798; APS_reductase.
IPR002500; PAPS_reduct.
IPR014729; Rossmann-like_a/b/a_fold.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1.

Pfam

PF01507; PAPS_reduct; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR02055; APS_reductase; 1.

ProtoNet

O33579.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Cytoplasm; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`<1 180`	`>180`	`Phosphoadenosine phosphosulfate reductase.`	`PRO_0000100641`
`NON_TER`	`1 1`

Sequence information

Length: 180 AA [This is the length of the partial sequence of the unprocessed precursor]

Molecular weight: 20395 Da [This is the MW of the partial sequence of the unprocessed precursor]

CRC64: F948C70505E461F4 [This is a checksum on the sequence]

        10         20         30         40         50         60 
LQTGRLFPET LKLIDETENQ YDIRISRYEP EQADIDAYAE KYGLNGFYES VEARHACCGV 

        70         80         90        100        110        120 
RKLKPLARAL SGATIWVTGL RRGQSANRAD TPFAEYDPER NLIKVNPLAD WDIDVIRAYV 

       130        140        150        160        170        180 
ADNGVPVNPL HQRGYPSIGC EPCTRAIKPG EPERAGRWWW ENDEKRECGL HVHEEAAAAQ

O33579 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools