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UniProtKB/Swiss-Prot entry O26156


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name IDSA_METTH
Primary accession number O26156
Secondary accession numbers None
Integrated into Swiss-Prot on July 15, 1998
Sequence was last modified on January 1, 1998 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 53)
Name and origin of the protein
Protein name Bifunctional short chain isoprenyl diphosphate synthase
Synonyms None
Includes Farnesyl pyrophosphate synthetase
     (FPP synthetase)
     (EC 2.5.1.1)
     (Dimethylallyltranstransferase)
Geranyltranstransferase
     (EC 2.5.1.10)
Gene name
Name: idsA
OrderedLocusNames: MTH_50
From
Methanobacterium thermoautotrophicum [TaxID: 187420] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Methanobacteria; Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Delta H;
PubMed=9371463 [NCBI, ExPASy, EBI, Israel, Japan]
Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R., Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N.;
"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics.";
J. Bacteriol. 179:7135-7155(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE000666; AAB84557.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR G69165; G69165.
RefSeq NP_275193.1; -.
3D structure databases
ModBase O26156.
Enzyme and pathway databases
BioCyc MTHE187420:MTH50-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0004161; Molecular function: dimethylallyltranstransferase activity (inferred from electronic annotation from EC).
GO:0004337; Molecular function: geranyltranstransferase activity (inferred from electronic annotation from EC).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0008299; Biological process: isoprenoid biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR000092; Polyprenyl_synt.
IPR017446; Polyprenyl_synth-rel.
IPR008949; Terpenoid_synth.
Graphical view of domain structure.
Gene3D G3DSA:1.10.600.10; Terpenoid_synth; 1.
PANTHER PTHR12001; Polyprenyl_synt; 1.
Pfam PF00348; polyprenyl_synt; 1.
Pfam graphical view of domain structure.
PROSITE PS00723; POLYPRENYL_SYNTHET_1; 1.
PS00444; POLYPRENYL_SYNTHET_2; 1.
ProtoNet O26156.
Genome annotation databases
GeneID 1470012; -.
GenomeReviews AE000666_GR; MTH_50.
KEGG mth:MTH50; -.
NMPDR fig|187420.1.peg.48; -.
Phylogenomic databases
HOGENOM O26156; -.
Genome annotation databases
CMR O26156; MTH_50.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Isoprene biosynthesis; Lipid synthesis; Magnesium; Multifunctional enzyme; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   325  325     Bifunctional short chain isoprenyl diphosphate synthase. PRO_0000123971
Sequence information
Length: 325 AA [This is the length of the unprocessed precursor] Molecular weight: 35485 Da [This is the MW of the unprocessed precursor] CRC64: BCF3A285A207916E [This is a checksum on the sequence]
        10         20         30         40         50         60 
MMEVMDILRK YSEMADERIR ESISDITPET LLRASEHLIT AGGKKIRPSL ALLSSEAVGG 

        70         80         90        100        110        120 
DPGDAAGVAA AIELIHTFSL IHDDIMDDDE IRRGEPAVHV LWGEPMAILA GDVLFSKAFE 

       130        140        150        160        170        180 
AVIRNGDSEM VKEALAVVVD SCVKICEGQA LDMGFEERLD VTEEEYMEMI YKKTAALIAA 

       190        200        210        220        230        240 
ATKAGAIMGG GSPQEIAALE DYGRCIGLAF QIHDDYLDVV SDEESLGKPV GSDIAEGKMT 

       250        260        270        280        290        300 
LMVVKALERA SEKDRERLIS ILGSGDEKLV AEAIEIFERY GATEYAHAVA LDHVRMAKER 

       310        320 
LEVLEESDAR EALAMIADFV LEREH 

O26156 in FASTA format

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