NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Reith M.E., Singh R.K., Curtis B., Boyd J., Bouevitch A., Kimball J., Munholland J., Murphy C., Sarty D., Williams J., Nash J., Johnson S., Brown L.;
"The genome sequence of Aeromonas salmonicida subsp. salmonicida A449.";
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: N-acetyl-L-glutamate 5-semialdehyde + NADP⁺ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH.
PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4 .
SUBCELLULAR LOCATION: Cytoplasm (Probable).
SIMILARITY: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000644; ABO88744.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_001140492.1; -.

3D structure databases

ModBase

A4SIM2.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0003942;	Molecular function: N-acetyl-gamma-glutamyl-phosphate reductase activity (inferred from electronic annotation from HAMAP).
GO:0006526;	Biological process: arginine biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

HAMAP

MF_00150; -; 1.
PBIL [Tree]

InterPro

IPR000706; AGPR_act_site.
IPR016040; NAD(P)-bd.
IPR000534; Semialdehyde_DHase_NAD-bd.
IPR012280; Semialdhyde_DHase_C.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.

Pfam

PF01118; Semialdhyde_dh; 1.
PF02774; Semialdhyde_dhC; 1.
Pfam graphical view of domain structure.

ProDom

PD003765; AGPR_act_site; 1.
[Domain structure / List of seq. sharing at least 1 domain]

TIGR01850; argC; 1.

PS01224; ARGC; 1.

Genome annotation databases

GeneID

4998422; -.

GenomeReviews

CP000644_GR; ASA_0578.

KEGG

asa:ASA_0578; -.

CMR

A4SIM2; ASA_0578.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Amino-acid biosynthesis; Arginine biosynthesis; Complete proteome; Cytoplasm; NADP; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 335`	`335`	`N-acetyl-gamma-glutamyl-phosphate reductase.`	`PRO_1000010972`
`ACT_SITE`	`156 156`		`By similarity.`

Sequence information

Length: 335 AA [This is the length of the unprocessed precursor]

Molecular weight: 35962 Da [This is the MW of the unprocessed precursor]

CRC64: A10FBA35A0572798 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MLNTVIVGAS GYAGAELAAL VQNHPQLKLF GLYVSAGSQD AHKRFSSLHP QWVGALDQPL 

        70         80         90        100        110        120 
LPLDEDGMTR ILTQADLVLL ATAHEVSAEL APKFLAKGLP VFDLSGAFRV KDQQFYSSFY 

       130        140        150        160        170        180 
GFTHENEQLL EQAAYGLAEW NSDAIAAAQL IAVPGCYPTA SLCALKPLQQ AGLIAEGWQP 

       190        200        210        220        230        240 
IINAVSGVSG AGRKAAINTS FCEVSLSPYG TFNHRHQPEI SHHLGKEVLF QPHLGNYVRG 

       250        260        270        280        290        300 
ILATIYVQMA DGVTPTQVDQ AFLKAYEGKP LVRLTGQMPS IRGVASTPYC DIAWQQQGNM 

       310        320        330 
LVVVSAIDNL LKGAASQAMQ CINIKFGFDP ATGLI

A4SIM2 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools