Species code:	LEPIN
Taxonomy:	Bacteria; Spirochaetes; Spirochaetales; Leptospiraceae; Leptospira (TaxID: 173) [NEWT/ NCBI]
Description:	Leptospira interrogans causes leptospirosis whose manifestations are fever, headache, malaise, myalgia, occasionally meningitidis, sometimes jaundice, renal insufficiency, anemia and hemorrhage of the skin. Rarely lethal. Worldwide spread except in polar regions. Contamination occurs through contact of the skin or mucous membranes with contaminated water, soil or vegetation or through direct contact with urine or tissues of infected animals. Farm and pet animals, including cattle, dogs, horses and swine, rats and other rodents act as the normal carrier host; wild animals, including deer, squirrels, foxes, skunks and even reptiles and amphibians may be infected.
Properties:	Presence of flagella: Yes Interaction: Animal pathogen in Mammalia Number of membranes: 2 Number of inteins: 1
Statistics:	Number of LEPIN entries in the UniProt Knowledgebase: 4690 (360 in UniProtKB/Swiss-Prot + 4330 in UniProtKB/TrEMBL)

Genome structure:	• Chromosome I EMBL accession number AE010300 (circular; 4,332,241 bp) (download entry) (download Genome Reviews). • Chromosome II EMBL accession number AE010301 (circular; 358,943 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] MEDLINE=22598143; PubMed=12712204; [ NCBI , EBI , Israel , Japan ] Ren S.-X., Fu G., Jiang X.-G., Zeng R., Miao Y.-G., Xu H., Zhang Y.-X., Xiong H., Lu G., Lu L.-F., Jiang H.-Q., Jia J., Tu Y.-F., Jiang J.-X., Gu W.-Y., Zhang Y.-Q., Cai Z., Sheng H.-H., Yin H.-F., Zhang Y., Zhu G.-F., Wan M., Huang H.-L., Qian Z., Wang S.-Y., Ma W., Yao Z.-J., Shen Y., Qiang B.-Q., Xia Q.-C., Guo X.-K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.-M., Shi M.-H., Chen Z., Xu J.-G., Zhao G.-P. ; "Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing."; Nature 422:888-893(2003).
Web links:	CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Leptospira&GLspecies=interrogans&GLstrain=56601 Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid189518%5Borgn%5D GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Lint_56601 Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Leptospira_interrogans.html LeptoList: http://bioinfo.hku.hk/GenoList/index.pl?database=leptolist PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p293_Lep_inter TIGR CMR: http://cmr.tigr.org/tigr-scripts/CMR/GenomePage.cgi?database=ntli02  EBI Proteome Analysis page

• Genome Proximity Viewer: This program displays the genes that are found in the genomic environment of a selected locus.
  
  
• Perform a BLAST search against all proteins from this proteome
  
  
• Download a file by FTP containing all UniProt Knowledgebase entries of this proteome
  • in UniProt Knowledgebase format
  • in FASTA format
  
  
• Retrieve set of characterized or identified proteins for this proteome
  
  
• Retrieve set of proteins with 3D structure for this proteome