Species code:	LACDB
Taxonomy:	Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus (TaxID: 321956) [NEWT/ NCBI]
Description:	Lactobacilli are normal inhabitants of the gastrointestinal tract of man and animals where they are widely considered to exert a number of beneficial roles including immunomodulation, interference with enteric pathogens, and maintenance of a healthy intestinal microflora. Historically, probiotic roles have been ascribed primarily to Lactobacillus acidophilus. The genus Lactobacillus presently comprises more than 50 recognized species of non pathogenic bacteria which in addition to their probiotic effects are useful to human as indispensable agents for the fermentation of foods and feed. Within the genus Lactobacillus, L. delbrueckii are part of the obligately homofermentative (Group I) cluster, which produce D-lactic acid from hexose sugars via the Embden-Meyerhof pathway and are incapable of fermenting pentoses. L. delbrueckii subsp. bulgaricus grows on a relatively restricted number of carbohydrates and typically requires pantothenic acid and niacin. L. delbrueckii subsp. bulgaricus is a component of thermophilic starter cultures used in the manufacture of a number of fermented dairy products. These cultures have an optimum growth temperature of approximately 42oC and contain Streptococcus thermophilus with L. delbrueckii subsp. bulgaricus and/or L. helveticus. These cultures are utilized in the yogurt, Swiss-type and Italian-type cheese varieties (adapted from http://genome.jgi-psf.org/draft_microbes/lacde/lacde.home.html).
Properties:	Presence of flagella: No Interaction: Animal commensal in Mammalia Number of membranes: 1 Number of inteins:0
Statistics:	Number of LACDB entries in the UniProt Knowledgebase: 1682 (208 in UniProtKB/Swiss-Prot + 1474 in UniProtKB/TrEMBL)

Genome structure:	Chromosome EMBL accession number CP000412 (circular; 1,856,951 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] PubMed=17030793; [ NCBI , EBI , Israel , Japan ] Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T., Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B.C., Mills D.A. ; "Comparative genomics of the lactic acid bacteria."; Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
Web links:	Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid321956%5Borgn%5D GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Ldel_BULGARICUS PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p403_Lac_delbr  EBI Proteome Analysis page

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