Species code:	ACTP7
Taxonomy:	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Actinobacillus (TaxID: 537457) [NEWT/ NCBI]
Description:	Actinobacillus pleuropneumoniae, a Gram-negative, non-motile, facultatively anaerobic Pasteurellaceae, causes porcine pleuropneumonia, a highly contagious disease for which there is no effective vaccine. There are least twelve different serotypes, some of which produce no disease but others cause severe disease. Serotypes vary in different countries. Types 1, 5, 9, 11 and 12 are usually highly virulent and strains 3 and 6 are mild. The bacterium is carried in the tonsils and upper respiratory tract. It is transmitted short distances by droplet infection and only survives outside the pig for a few days. Strain AP76 was isolated from a diseased pig lung in Canada. It is serotype 7 and is a strain in which spontaneous chromosomal deletions have been shown to occur. It encodes insertion elements that have been shown to interfere with detection of infected vs. vaccinated animals as it inserts into serological antigens used to detect infection.
Properties:	Presence of flagella: No Interaction: Animal pathogen in Mammalia Number of membranes: 2 Number of inteins:0
Statistics:	Number of ACTP7 entries in the UniProt Knowledgebase: 2113 (334 in UniProtKB/Swiss-Prot + 1779 in UniProtKB/TrEMBL)

Genome structure:	• Chromosome EMBL accession number CP001091 (circular; 2,331,981 bp) (download entry) (download Genome Reviews). • Plasmid APP7_A EMBL accession number CP001094 (circular; 5,685 bp) (download entry) (download Genome Reviews). • Plasmid ABB7_B EMBL accession number CP001093 (circular; 4,236 bp) (download entry) (download Genome Reviews). • Plasmid APP7_C EMBL accession number CP001092 (circular; 3,533 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] Linke B., Buettner F., Martinez-Arias R., Goesmann A., Baltes N., Tegetmeyer H., Singh M., Gerlach G.F. ; "Genome and proteome analysis of A. pleuropneumoniae serotype 7."; Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
Web links:	Official genome site(s): http://gib.genes.nig.ac.jp/single/index.php?spid=Aple_AP76 Other web sites: Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=29909  EBI Proteome Analysis page

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