PROSITE - Entry: PS50847

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Entry: PS50847

General information about the entry
Entry name	GRAM_POS_ANCHORING
Accession number	PS50847
Entry type	MATRIX
Date	MAY-2002 (CREATED); MAY-2002 (DATA UPDATE); AUG-2008 (INFO UPDATE).
PROSITE Documentation	PDOC00373
Associated ProRule	PRU00477
Name and characterization of the entry
Description	Gram-positive cocci surface proteins LPxTG motif profile.
Matrix / Profile	/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=38; /DISJOINT: DEFINITION=PROTECT; N1=4; N2=35; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=-1.1366972; R2=0.0260992; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=370; N_SCORE=8.5000; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=293; N_SCORE=6.5000; MODE=1; TEXT='?'; /DEFAULT: M0=-9; D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105; A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='L'; M=-10,-30,-20,-30,-20,-10,-30,-20,-20,-60, 60,-20,-30,-50,-20,-20,-30,-10,-10,-19,-10,-20; /M: SY='P'; M= -8,-20,-39,-10,-10,-30,-19,-20,-20,-10,-29,-20,-20, 87,-10,-20, -9,-10,-29,-30,-30,-10; /M: SY='E'; M= 0, 6,-22, 6, 8,-23,-12, 0,-28, 6, 0,-12, 8,-12, 7,-10, 3, 5,-17,-28,-13, 7; /M: SY='T'; M= 20,-10,-10,-10,-10,-11,-18,-20,-10,-10,-11,-10,-10,-10,-10,-11, 36, 50,-10,-30,-11,-10; /M: SY='G'; M= 60,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20, 50,-20,-20,-20, 45,-20,-30,-20,-30,-20; /M: SY='E'; M= -5, 13,-24, 19, 23,-27, -7, -6,-26, -1,-21,-19, 5, -8, 4, -7, 6, -1,-21,-32,-19, 13; /M: SY='E'; M= 1, 5,-21, 2, 8,-22,-13, -6,-18, 5,-19,-20, 7,-20, 4, -1, 6, 3,-14,-29,-15, 5; /M: SY='N'; M= 1, 6,-21, 4, 3,-21, -4, -7,-27,-10,-19,-13, 8,-12, 0, -4, 6, -1,-16,-29,-16, 1; /M: SY='N'; M= -2, 10,-19, 4, 3,-20, -7, -3,-17, -3,-21,-13, 17,-20, 2, -5, 12, 7,-16,-33,-16, 2; /M: M= 0, -9,-22,-12, -9,-12,-16,-13, -4,-10, -7, -5, -4, -3, -9,-12, -2, 0, -5,-25,-11,-11; /M: SY='F'; M= -6,-14,-22,-18,-14, 6,-18,-14, -1,-15, 0, -2, -9,-15,-14,-14, -7, -3, -3,-14, 1,-14; /M: SY='F'; M= -8,-20,-20,-25,-18, 17,-20,-15, 3,-20, 12, 6,-15,-20,-18,-16,-12, -4, 0,-13, 5,-18; /M: SY='T'; M= 0,-10,-18,-15,-10, -8,-16,-17, -2,-12, -1, -2, -8,-11,-11,-13, 1, 10, 0,-25,-10,-11; /M: SY='I'; M= 6,-20,-18,-26,-20, -2,-18,-21, 13,-20, 10, 7,-17,-20,-17,-20, -8, -2, 12,-21, -6,-19; /M: SY='A'; M= 15,-17,-15,-23,-16, -7,-13,-21, 4,-17, 7, 2,-16,-17,-16,-19, -3, 2, 9,-22,-11,-16; /M: SY='G'; M= 10,-13,-23,-17,-18,-16, 32,-20,-22,-18,-15,-11, -7,-19,-18,-19, -1,-12,-15,-17,-20,-18; /M: SY='L'; M= 7,-19,-18,-23,-18, -5, -8,-20, 3,-21, 10, 3,-16,-20,-17,-19, -8, -4, 4,-21,-10,-18; /I: I=-4; MI=0; MD=-22; IM=0; DM=-22; /M: SY='L'; M= -3,-24,-18,-27,-20, 2,-24,-21, 17,-23, 24, 14,-22,-24,-18,-19,-14, -2, 15,-23, -5,-19; /M: SY='M'; M= -1,-21,-17,-26,-19, 3,-20,-18, 12,-20, 13, 14,-18,-22,-16,-18, -9, -1, 11,-22, -4,-18; /M: SY='A'; M= 10,-18,-16,-23,-17, -5,-13,-20, 6,-18, 7, 4,-15,-19,-15,-18, -3, 1, 8,-23,-10,-16; /M: SY='V'; M= 5,-18,-18,-23,-19, -4,-10,-22, 5,-20, 6, 2,-15,-20,-18,-19, -5, 0, 8,-22,-10,-19; /M: SY='A'; M= 9,-17,-19,-21,-17,-10, 0,-21, -1,-20, 3, -1,-13,-20,-16,-20, -3, -3, 2,-23,-13,-17; /M: SY='G'; M= 9,-10,-23,-12,-16,-23, 37,-19,-26,-17,-21,-15, -3,-15,-16,-18, 5, -8,-17,-23,-24,-16; /M: SY='L'; M= 4,-20,-17,-24,-19, -2,-10,-20, 5,-21, 9, 4,-16,-22,-18,-20, -7, -4, 6,-21, -8,-19; /M: SY='L'; M= -1,-22,-19,-25,-20, 6,-13,-19, 6,-21, 11, 5,-18,-24,-20,-18,-11, -6, 7,-16, -2,-20; /M: SY='L'; M= -1,-24,-18,-28,-21, 8,-22,-21, 12,-24, 21, 8,-22,-25,-20,-20,-16, -5, 9,-15, 0,-20; /M: SY='L'; M= -2,-21,-18,-24,-19, 9,-16,-18, 4,-20, 11, 3,-18,-24,-19,-17,-10, -3, 6,-16, 1,-19; /M: SY='V'; M= -1,-16,-21,-19,-13, -3,-14,-17, -2, -7, 0, 0,-12,-20,-12, -7, -7, -4, 1,-19, -5,-13; /M: SY='K'; M= -8, -9,-26,-10, -2,-18,-16,-11,-18, 20,-15, -6, -6,-16, -1, 19, -9, -8,-10,-21,-15, -2; /M: SY='R'; M=-13, -3,-28, -5, 2,-22,-16, -4,-27, 29,-24,-11, 3,-15, 6, 39, -6, -8,-19,-20,-10, 2; /M: SY='R'; M=-14, -5,-28, -5, 5,-24,-19, -3,-27, 32,-22, -9, 1,-16, 10, 45, -8, -9,-19,-21,-10, 5; /M: SY='K'; M=-11, 4,-29, 4, 15,-28,-18, -5,-29, 33,-26,-13, 4,-11, 11, 28, -6, -8,-22,-24,-13, 12; /M: SY='E'; M= -7, 6,-25, 7, 17,-25,-16, -5,-23, 15,-22,-13, 6,-10, 9, 10, 1, -2,-19,-27,-14, 12; /M: SY='D'; M= -7, 18,-24, 19, 12,-26, -9, 1,-25, 4,-23,-17, 16,-13, 4, -1, 4, -4,-21,-33,-16, 8; /M: SY='K'; M= -9, 8,-23, 9, 13,-28,-14, -4,-25, 17,-24,-13, 7,-12, 9, 8, -1, -6,-20,-28,-15, 11; /M: SY='N'; M= 0, 11,-19, 5, 5,-24, -7, -5,-21, 7,-23,-14, 16,-14, 3, 0, 5, -2,-19,-30,-17, 4; /M: SY='K'; M= -7, 2,-26, 3, 10,-21,-18, -8,-19, 16,-14, -8, 0,-13, 5, 7, -7, -9,-16,-24,-11, 7; /M: SY='A'; M= 1, -1,-22, -4, 1,-11,-11, -4,-19, 0,-14,-10, 0,-15, -2, -1, -2, -5,-15,-21, -9, -1; /I: E1=0; IE=-105; DE=-105;
Numerical results
UniProtKB/Swiss-Prot release number: 56.1, total number of sequence entries in that release: 397539. Total number of hits in UniProtKB/Swiss-Prot: 160 hits in 160 different sequences Number of hits on proteins that are known to belong to the set under consideration: 157 hits in 157 different sequences Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences Number of false hits (on unrelated proteins): 3 hits in 3 different sequences Number of known missed hits: 17 Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 2 Precision (true hits / (true hits + false positives)): 98.12 % Recall (true hits / (true hits + false negatives)): 90.23 %
Comments
MATRIX_TYPE: protein_domain Scaling database: UniProtKB/Swiss-Prot: reversed Matrix author: C_Lachaize, CJA_Sigrist Taxonomic range: Prokaryotes (Bacteria) Maximum known number of repetitions of the pattern in a single protein: 1 VERSION: 1
Cross-references
UniProtKB/Swiss-Prot	True positive hits: ARP4_STRPY (P13050), ASA1_ENTFA (P17953), BAG_STRAG (P27951), BBP_STAAR (Q6GJA6), BBP_STAAU (Q14U76), BCA_STRA1 (Q02192), C5AP_STRP3 (Q8K5Q0), C5AP_STRP6 (Q5X9R0), C5AP_STRP8 (Q8NZ80), C5AP_STRPY (P15926), CLFA_STAA8 (Q2G015), CLFA_STAAC (Q5HHM8), CLFA_STAAE (Q53653), CLFA_STAAM (Q932C5), CLFA_STAAN (Q99VJ4), CLFA_STAAR (Q6GIK4), CLFA_STAAS (Q6GB45), CLFA_STAAW (Q8NXJ1), CLFB_STAA8 (Q2FUY2), CLFB_STAAC (Q5HCR7), CLFB_STAAE (O86476), CLFB_STAAM (Q99R07), CLFB_STAAN (Q7A382), CLFB_STAAR (Q6GDH2), CLFB_STAAS (Q6G644), CLFB_STAAW (Q8NUL0), DEXT_STRDO (P39653), DEXT_STRMU (Q54443), FBE_STAEP (O70022), FM1_ACTVI (P18477), FM2_ACTNA (P12616), FNBA_STAA1 (A7X6I5), FNBA_STAA3 (Q2FE03), FNBA_STAA8 (P14738), FNBA_STAAB (Q2YW62), FNBA_STAAC (Q5HD51), FNBA_STAAM (Q99RD2), FNBA_STAAN (Q7A3J7), FNBA_STAAR (Q6GDU5), FNBA_STAAS (Q6G6H3), FNBA_STAAW (Q8NUU7), IGA1A_STRPN (Q97QP7), IGA1B_STRPN (Q54875), IGA1_STRR6 (Q59947), IGA1_STRSA (Q59986), INLA_LISMF (Q723K6), INLA_LISMO (P25146), INLI_LISMF (Q723X5), INLI_LISMO (Q8YA32), INLJ_LISMF (Q71VU0), INLJ_LISMO (Q8Y3L4), ISDA_STAA1 (A7X148), ISDA_STAA2 (A6U0U7), ISDA_STAA3 (Q2FHV1), ISDA_STAA8 (Q2FZE9), ISDA_STAA9 (A5IS16), ISDA_STAAB (Q2YX95), ISDA_STAAC (Q5HGV4), ISDA_STAAE (A6QG31), ISDA_STAAM (Q99UX4), ISDA_STAAN (Q7A655), ISDA_STAAR (Q6GHV6), ISDA_STAAS (Q6GA85), ISDA_STAAT (A8Z1R0), ISDA_STAAU (P0C1S5), ISDA_STAAW (Q7A152), ISDB_STAA1 (A7X146), ISDB_STAA2 (A6U0U6), ISDB_STAA3 (Q2FHV2), ISDB_STAA8 (Q2FZF0), ISDB_STAA9 (A5IS15), ISDB_STAAB (Q2YX96), ISDB_STAAC (Q5HGV5), ISDB_STAAE (A6QG30), ISDB_STAAM (Q99UX5), ISDB_STAAN (Q7A656), ISDB_STAAR (Q6GHV7), ISDB_STAAS (Q6GA86), ISDB_STAAT (P0C7J5), ISDB_STAAW (Q8NX66), M12_STRPY (P19401), M21_STRPY (P50468), M22_STRPY (P50469), M24_STRPY (P12379), M49_STRP9 (P16947), M5_STRP5 (P02977), M6A_STRP6 (Q5X9Q9), M6B_STRP6 (P08089), MRP4_STRPY (P30141), MRP_STRSU (P32653), MX_STRP9 (P16946), NANA_STRPN (P62575), NANA_STRR6 (P62576), P1P_LACLC (P16271), P2P_LACLC (P15293), P2P_LACPA (Q02470), P3P_LACLS (P15292), PAB_PEPMA (Q51911), PAC_STRMU (P11657), PLS_STAAC (Q5HJU7), PLS_STAAM (Q931E9), PLS_STAAN (P61598), PLS_STAAU (P80544), PLS_STAAW (Q8NUV0), PLS_STAES (Q8CQD9), SASG_STAA8 (Q2G2B2), SDRC_STAA3 (Q2FJ79), SDRC_STAA8 (Q2G0L5), SDRC_STAAC (Q5HIB4), SDRC_STAAE (O86487), SDRC_STAAM (Q99W48), SDRC_STAAN (Q7A781), SDRC_STAAR (Q6GJA7), SDRC_STAAS (Q6GBS6), SDRC_STAAW (Q8NXX7), SDRD_STAA3 (Q2FJ78), SDRD_STAA8 (Q2G0L4), SDRD_STAAC (Q5HIB3), SDRD_STAAE (O86488), SDRD_STAAM (Q99W47), SDRD_STAAN (Q7A780), SDRD_STAAS (Q6GBS5), SDRD_STAAW (Q8NXX6), SDRE_STAA3 (Q2FJ77), SDRE_STAAC (Q5HIB2), SDRE_STAAE (O86489), SDRE_STAAM (Q932F7), SDRE_STAAN (Q99W46), SDRE_STAAS (Q6GBS4), SDRE_STAAW (Q8NXX5), SDRF_STAEP (Q9KI14), SDRF_STAES (Q8CMP4), SDRG_STAEP (Q9KI13), SDRI_STASA (Q8KWM1), SPA1_STAA8 (P02976), SPA2_STAAU (P38507), SPAA_STRDO (P21979), SPAP_STRMU (P23504), SPA_STAAM (P0A015), SPA_STAAN (P99134), SPG1_STRSG (P06654), SPG2_STRSG (P19909), SPH_STRP1 (P50470), SRAP_STAA3 (Q2FDK5), SRAP_STAA8 (Q2FUW1), SRAP_STAAC (Q5HCP3), SRAP_STAAM (Q99QY4), SRAP_STAAN (Q7A362), SRAP_STAAR (Q6GDE9), SRAP_STAAS (Q6G620), SRAP_STAAU (Q8VQ99), SRAP_STAAW (Q8NUJ3), SRAP_STAHJ (Q4L9P0), SSP5_STRGN (P16952), STRH_STRPN (P49610), TEE6_STRP6 (P18481), WAPA_STRMU (P11000) False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile): C5AP_STRP1 (P58099), CNA_STAAU (Q53654), FRUA_STRMU (Q03174), HYSA_STRPN (Q54873), ISDH_STAA3 (Q2FG07), ISDH_STAA8 (Q2FXJ2), ISDH_STAAB (Q2YTF7), ISDH_STAAC (Q5HF43), ISDH_STAAM (Q931P4), ISDH_STAAN (Q99TD3), ISDH_STAAS (Q6G8J7), ISDH_STAAW (Q8NW39), NISP_LACLA (Q07596), UAFA_STAS1 (Q4A0V8), ZMPB_STRPN (Q9L7Q2), ZMPB_STRR6 (Q8DQN5), ZMPC_STRPN (Q97T80) `Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences): M32_STRTR (P83330), PAM_STRPY (P49054) False positive hits (sequences which do not belong to the set under consideration): LRFN6_HUMAN (Q5R3F8), LRFN6_MOUSE (Q68FM6), MRC2_RAT (Q4TU93) Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment

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