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Publications from 1985 until 1997

I. Articles in journals with editorial policy

  1. Hochstrasser D, Augsburger V, Funk M, Appel R, Pellegrini C, Muller AF. Immobilized pH gradients in capillary tubes and two-dimensional gel electrophoresis. Electrophoresis 1986; 7: 505-511.

  2. Hochstrasser D, Roux P, Dayer JM, Cruchaud A, Appel R, Funk M, Pellegrini C, Muller AF. Cartographies protéiques de cellules circulantes normales: lymphocytes et monocytes. Schweiz Med Wochenschr 1986; 116: 1773-1775.

  3. Appel R, Hochstrasser D, Roch C, Funk M, Muller AF, Pellegrini C. Automatic classification of two-dimensional gel electrophoresis pictures by heuristic clustering analysis: a step toward machine learning. Electrophoresis 1988; 9: 136-142.

  4. James RW, Hochstrasser D, Tissot JD, Funk M, Appel R, Barja F, Pellegrini C, Muller AF, Pometta D. Protein heterogeneity of lipoprotein particles containing apolipoprotein A-I without apolipoprotein A-II and apolipoprotein A-I with apolipoprotein A-II isolated from human plasma. J Lipid Res 1988; 29: 1557-1571.

  5. Pun T, Hochstrasser DF, Appel RD, Funk M, Villars-Augsburger V, Pellegrini C. Computerized classification of two-dimensional gel electrophoretograms by correspondence analysis and ascendant hierarchical clustering. Appl Theor Electrophor 1988; 1: 3-9.

  6. Hochstrasser DF, Funk M, Appel RD, Pun T, James RW, Hochstrasser AC, Scherrer JR, Pellegrini C, Muller AF. From biopsy to automatic diagnosis. Schweiz Med Wochenschr 1990; 120: 1862-1866.

  7. Appel RD, Hochstrasser DF, Funk M, Vargas JR, Pellegrini C, Muller AF, Scherrer JR. The MELANIE project: from a biopsy to automatic protein map interpretation by computer. Electrophoresis 1991; 12: 722-735.

  8. Hochstrasser DF, Appel RD, Vargas R, Perrier R, Vurlod JF, Ravier F, Pasquali C, Funk M, Pellegrini C, Muller AF, . A clinical molecular scanner: the Melanie project. MD Comput 1991; 8: 85-91.

  9. Jaconi ME, Theler JM, Schlegel W, Appel RD, Wright SD, Lew PD. Multiple elevations of cytosolic-free Ca2+ in human neutrophils: initiation by adherence receptors of the integrin family. J Cell Biol 1991; 112: 1249-1257.

  10. Hochstrasser DF, Frutiger S, Paquet N, Bairoch A, Ravier F, Pasquali C, Sanchez JC, Tissot JD, Bjellqvist B, Vargas R, Appel RD, Hughes GJ. Human liver protein map: A reference database established by microsequencing and gel comparison. Electrophoresis 1992; 13: 992-1001.

  11. Appel RD, Sanchez JC, Bairoch A, Golaz O, Miu M, Vargas JR, Hochstrasser DF. SWISS-2DPAGE: a database of two-dimensional gel electrophoresis images. Electrophoresis 1993; 14: 1232-1238.

  12. Golaz O, Hughes GJ, Frutiger S, Paquet N, Bairoch A, Pasquali C, Sanchez JC, Tissot JD, Appel RD, Walzer C, . Plasma and red blood cell protein maps: update 1993. Electrophoresis 1993; 14: 1223-1231.

  13. Hughes GJ, Frutiger S, Paquet N, Pasquali C, Sanchez JC, Tissot JD, Bairoch A, Appel RD, Hochstrasser DF. Human liver protein map: update 1993. Electrophoresis 1993; 14: 1216-1222.

  14. Appel RD, Bairoch A, Hochstrasser DF. A new generation of information retrieval tools for biologists: the example of the ExPASy WWW server. Trends Biochem Sci 1994; 19: 258-260.

  15. Appel RD, Sanchez JC, Bairoch A, Golaz O, Ravier F, Pasquali C, Hughes GJ, Hochstrasser DF. The SWISS-2DPAGE database of two-dimensional polyacrylamide gel electrophoresis. Nucleic Acids Res 1994; 22: 3581-3582.

  16. Cremona O, Muda M, Appel RD, Frutiger S, Hughes GJ, Hochstrasser DF, Geinoz A, Gabbiani G. Differential protein expression in aortic smooth muscle cells cultured from newborn and aged rats. Exp Cell Res 1995; 217: 280-287.

  17. Hochstrasser DF, Appel RD, Golaz O, Pasquali C, Sanchez JC, Bairoch A. Sharing of worldwide spread knowledge using hypermedia facilities & fast communication protocols (Mosaic and World Wide Web): the example of ExPASy. Methods Inf Med 1995; 34: 75-78.

  18. Sanchez JC, Appel RD, Golaz O, Pasquali C, Ravier F, Bairoch A, Hochstrasser DF. Inside SWISS-2DPAGE database. Electrophoresis 1995; 16: 1131-1151.

  19. Appel RD, Sanchez JC, Bairoch A, Golaz O, Ravier F, Pasquali C, Hughes GJ, Hochstrasser DF. The SWISS-2DPAGE database of two-dimensional polyacrylamide gel electrophoresis, its status in 1995. Nucleic Acids Res 1996; 24: 180-181.

  20. Appel RD, Bairoch A, Sanchez JC, Vargas JR, Golaz O, Pasquali C, Hochstrasser DF. Federated two-dimensional electrophoresis database: a simple means of publishing two-dimensional electrophoresis data. Electrophoresis 1996; 17: 540-546.

  21. Golaz O, Wilkins MR, Sanchez JC, Appel RD, Hochstrasser DF, Williams KL. Identification of proteins by their amino acid composition: an evaluation of the method. Electrophoresis 1996; 17: 573-579.

  22. Mascarini C, Ratib O, Trayser G, Ligier Y, Appel RD. In-house access to PACS images and related data through World Wide Web. Eur J Radiol 1996; 22: 218-220.

  23. Pasquali C, Frutiger S, Wilkins MR, Hughes GJ, Appel RD, Bairoch A, Schaller D, Sanchez JC, Hochstrasser DF. Two-dimensional gel electrophoresis of Escherichia coli homogenates: the Escherichia coli SWISS-2DPAGE database. Electrophoresis 1996; 17: 547-555.

  24. Sanchez JC, Golaz O, Frutiger S, Schaller D, Appel RD, Bairoch A, Hughes GJ, Hochstrasser DF. The yeast SWISS-2DPAGE database. Electrophoresis 1996; 17: 556-565.

  25. Wilkins MR, Ou K, Appel RD, Sanchez JC, Yan JX, Golaz O, Farnsworth V, Cartier P, Hochstrasser DF, Williams KL, Gooley AA. Rapid protein identification using N-terminal "sequence tag" and amino acid analysis. Biochem Biophys Res Commun 1996; 221: 609-613.

  26. Wilkins MR, Hochstrasser DF, Sanchez JC, Bairoch A, Appel RD. Integrating two-dimensional gel databases using the Melanie II software. Trends Biochem Sci 1996; 21: 496-497.

  27. Wilkins MR, Sanchez JC, Gooley AA, Appel RD, Humphery-Smith I, Hochstrasser DF, Williams KL. Progress with proteome projects: why all proteins expressed by a genome should be identified and how to do it. Biotechnol Genet Eng Rev 1996; 13: 19-50.

  28. Wilkins MR, Pasquali C, Appel RD, Ou K, Golaz O, Sanchez JC, Yan JX, Gooley AA, Hughes G, Humphery-Smith I, Williams KL, Hochstrasser DF. From proteins to proteomes: large scale protein identification by two-dimensional electrophoresis and amino acid analysis. Biotechnology (N Y ) 1996; 14: 61-65.

  29. Appel RD, Vargas JR, Palagi PM, Walther D, Hochstrasser DF. Melanie II--a third-generation software package for analysis of two-dimensional electrophoresis images: II. Algorithms. Electrophoresis 1997; 18: 2735-2748.

  30. Appel RD, Palagi PM, Walther D, Vargas JR, Sanchez JC, Ravier F, Pasquali C, Hochstrasser DF. Melanie II--a third-generation software package for analysis of two-dimensional electrophoresis images: I. Features and user interface. Electrophoresis 1997; 18: 2724-2734.

  31. Boyer C, Baujard O, Baujard V, Aurel S, Selby M, Appel RD. Health On the Net automated database of health and medical information. Int J Med Inform 1997; 47: 27-29.

  32. Hoogland C, Baujard V, Sanchez JC, Hochstrasser DF, Appel RD. Make2ddb: a simple package to set up a two-dimensional electrophoresis database for the World Wide Web. Electrophoresis 1997; 18: 2755-2758.

  33. Peitsch MC, Wilkins MR, Tonella L, Sanchez JC, Appel RD, Hochstrasser DF. Large-scale protein modelling and integration with the SWISS-PROT and SWISS-2DPAGE databases: the example of Escherichia coli. Electrophoresis 1997; 18: 498-501.

  34. Sanchez JC, Wirth P, Jaccoud S, Appel RD, Sarto C, Wilkins MR, Hochstrasser DF. Simultaneous analysis of cyclin and oncogene expression using multiple monoclonal antibody immunoblots. Electrophoresis 1997; 18: 638-641.

  35. Wilkins MR, Lindskog I, Gasteiger E, Bairoch A, Sanchez JC, Hochstrasser DF, Appel RD. Detailed peptide characterization using PEPTIDEMASS--a World-Wide-Web-accessible tool. Electrophoresis 1997; 18: 403-408.

II. Books, book chapters & guest edition

  1. Appel RD. MELANIE - un système d'analyse et d'interprétation automatique d'images de gels d'électrophorèse bidimensionnelle; systèmes experts et apprentissage automatique. Thèse de doctorat ès sciences, mention informatique (Université de Genève). Le concept moderne/Editions; 1988; ISBN: 2-88242-003-X.

  2. Appel RD. Interfacing and Integrating Databases. In: Wilkins MR, Williams KL, Appel RD, Hochstrasser DF, eds. Proteome research: new frontiers in functional genomics. Berlin Heidelberg: Springer Verlag; 1997: 149-175.

  3. Appel RD, Dunn MJ, Hochstrasser DF. Special issue on Biomedicine and Biocomputing (Guest edition). Electrophoresis, Vol.18, No. 15; 1997.

  4. Sanchez JC, Wilkins M, Appel RD, Hochstrasser DF. Identifying Proteins for Proteome Studies. In: Creighton ET, ed. Protein Function: a practical approach (second edition). IRL Press; 1997: 1-27.

  5. Wilkins MR, Williams KL, Appel RD, Hochstrasser DF. Proteome research: new frontiers in functional genomics. Berlin Heidelberg, Springer Verlag; 1997.

III. Articles in journals without editorial policy

  1. Pellegrini C, Funk M, Appel RD. Le traitement de l'image. Cahiers de la faculté des sciences 1985; 3-14.

  2. Pellegrini C, Hochstrasser D, Appel R, Funk M. Informatique et électrophorèse : de l'image d'une biopsie tissulaire au diagnostic automatique. Fonds National Suisse de la Recherche Scientifique 1987.

  3. Hochstrasser D, Funk M, Appel R, James R, Hochstrasser AC, Scherrer JR, Pellegrini C, Muller AF. Applications Cliniques de l'Electrophorèse Bidimensionnelle. Spectra Biologie 1990; 90/1: 45-46.

  4. Appel RD, Hochstrasser DF, Bairoch A. Electrophorèse bidimensionnelle et informatique: un outil pour le diagnostic médical? Labolife 1993; 4: 7-8.

  5. Appel RD, Hochstrasser DF, Pellegrini C. Le projet Melanie. Cahier spécial de la Faculté des Sciences 1993.

  6. Hochstrasser DF, Sanchez JC, Golaz O, Tissot JD, Appel RD. Cartographie protéique du sérum et du plasma. Méd & Hyg 1995; 53: 988-992.

  7. Bairoch A, Appel RD, Peitsch MC. The ExPASy WWW Server - a Tool for Proteome Research. Protein Data Bank Quaterly Newsletter 1997; 81: 5-7.

IV. Conference proceedings

  1. Appel R, Funk M, Hochstrasser D, Pellegrini C, Muller AF. A computerized system for spot detection and analysis of two-dimensional electrophoresis images. In: Thalmann N, Thalmann D, eds. Computer-generated images (the state of the art) (Proceedings of Graphics Interface, Toronto 1985). Tokyo: Springer-Verlag; 1985: 118-124.

  2. Appel R, Funk M, Hochstrasser D, Muller AF, Pellegrini C. Un système expert d'aide à l'analyse et l'interprétation d'images médicales. Cognitiva. Paris: 1985.

  3. Appel R, Funk M, Hochstrasser D, Muller AF, Pellegrini C. Un système interactif de traitement d'images d'électrophorèse bidimensionnelle. International Electronic Image Week. Nice: Apr. 1986.

  4. Appel R, Funk M, Hochstrasser D, Muller AF, Pellegrini C. Mélanie, un système expert d'aide à l'analyse et à l'interprétation d'électrophorèses bidimensionnelles. In: Galteau, Siest, eds. Progrès Récents en Electrophorèse Bidimensionnelle. Presses Universitaires de Nancy; 1986: 107-116.

  5. Hochstrasser D, Funk M, Appel R, Pellegrini C, Muller AF. Clinical application of automatic computer comparison of 2 D. gel electrophoresis images: diagnosis of Waldenström macroglobulinemia ? In: Galteau, Siest, eds. Progrès Récents en Electrophorèse Bidimensionnelle. Presses Universitaires de Nancy; 1986: 117-120.

  6. Hochstrasser D, Maignan MF, Dumont JM, Funk M, Appel R, Pellegrini C, Muller AF. CCL4 induced cirrhosis of the liver: 2 dimensional gel electrophoretic analysis; biochemical and histological correlation. In: Dunn M, ed. Electrophoresis '86. VCH Publishers; 1986: 598-602.

  7. Hochstrasser D, Augsburger V, Funk M, Appel R, Pellegrini C, Muller AF. Immobilized pH gradients in capillary tubes : effect of immobilines dilution on 2 dimensional gel pictures. In: Dunn M, ed. Electrophoresis '86. VCH Publishers; 1986: 566-568.

  8. Funk M, Appel R, Roch C, Hochstrasser D, Pellegrini C, Muller AF. Knowledge acquisition in expert system assisted diagnosis : a machine learning approach. In: Fox J, Fieschi M, Engelbrecht R, eds. Lecture Notes in Medical Informatics (proceedings AIME, Marseille 1987). Springer-Verlag; 1987.

  9. Appel RD, Komorowski HJ, Barr CE, Greenes RA. Intelligent Focusing in Knowledge Indexing and Retrieval - The Relatedness Tool. Symposium on Computer Applications in Medical Care. Washington: Nov. 1988.

  10. Hochstrasser DF, Funk M, Appel RD, Scherrer JR, Pellegrini C, Muller AF. Les techniques d'intelligence artificielle dans l'analyse des électrophorèses bidimensionnelles. Journées Franc. d'IA. Montpelier: 1988.

  11. Hochstrasser D, Funk M, Appel RD, James R, Hochstrasser AC, Scherrer JR, Pellegrini C, Muller AF. Clinical applications of two-dimensional polyacrylamide gel electrophoresis. Electrophoresis forum '89. 1989: 134-136.

  12. Appel RD, Ratib O, Scherrer JR. Champolion : an Image File Format Translator. Picture Archiving and Communication Systems (PACS) in Medicine. Evian, France: Oct. 1990.

  13. Appel RD, Ratib O, Scherrer JR. The Use of a File Format Description Language for easy Handling of Images from Multiple Sources. EuroPACS meeting. Trieste: 1990.

  14. Hochstrasser D, Ratib O, Funk M, Appel R, Scherrer JR. Images en Médecine Clinique et en Médecine Fondamentale. Journées Francophones d'Informatique Médicale. Nîmes: 1990: 231-234.

  15. Ratib O, Ligier Y, Appel R, Scherrer JR. Papyrus: a portable image file format. Picture Archiving and Communication Systems (PACS) in Medicine. Evian, France: Oct. 1990.

  16. Appel RD, Brunet D, Funk M, Hochstrasser DF. Improving automatic matching of 2D-PAGE images. 2D-PAGE' 1991, Proc. Int. Meeting on Two-Dimensional Electrophoresis. London: July 1991: 58-62.

  17. Burke P, Appel RD, Funk M, Vargas R, Hochstrasser D, Scherrer JR. The Application of Distributed Articificial Intelligence to Medical Diagnosis. AIME 91, Proc. 3rd Conference on AI in Medicine, Maastricht, Netherlands, June 1991. Springer Verlag; 1991: 160-172.

  18. Goodman AM, Burke P, Funk M, Vargas RJ, Snydr-Michal JT, Appel RD, Hochstrasser DF. A model for a distributed database to manage large 2D-PAGE collaborative experiments. 2D-PAGE' 1991, Proc. Int. Meeting on Two-Dimensional Electrophoresis. London: July 1991: 73-77.

  19. Hochstrasser DF, Appel RD, Vargas R, Perrier R, Ravier F, Funk M, Pellegrini C, Muller AF, Scherrer JR. Clinical molecular scanner : The Melanie project. Proceedings of HICSS-24. Hawaii: 1991: 626-635.

  20. Hochstrasser DF, Huber O, Kaelin K, Touss A, Pavlovic A, Funk M, Appel RD, Pasquali C, Ravier F, Tissot JD, Goodman A, Muller AF. Clinical Application of Two Dimensional Polyacrylamide Gel Electrophoresis: Its Future. 2D-PAGE' 1991, Proc. Int. Meeting on Two-Dimensional Electrophoresis. London: July 1991: 224-229.

  21. Alpay LL, Appel RD, Hochstrasser DF. Building an Expert System for Obtaining Diagnoses from Protein Maps. MEDINFO 92. Geneva: Sept. 1992: 649-652.

  22. Burke P, Appel RD, Vargas JR, Alpay LL, Pellegrini C, Scherrer JR, Hochstrasser DF. Computer Assisted Analysis of Two-Dimensional Polyacrylamide Gel Electrophoresis. MEDINFO 92. Geneva: Sept. 1992: 312-317.

  23. Burke P, Appel RD, Funk M, Hochstrasser DF, Scherrer JR. Can AI Help the Physician ? Third Annual Meeting of the Swiss Group for Artificial Intelligence and Cognitive Science SGAICO'91. Mar. 1992: 49-59.

  24. Hochstrasser DF, Appel RD, Burke P, Goodman A, Snydr-Michal J, Vargas JR, Ratib O, Pellegrini C, Scherrer JR. L'Imagerie dans le diagnostic médical - l'exemple du système Melanie. Journées Francophones d'Informatique. Genève: Apr. 1992.

  25. Appel RD, Bologna G, Hochstrasser DF. Classification tools for Diagnostic Rule Formation from Protein Maps. Proceedings of MIE 93, Jerusalem, April 18-22, 1993. Freund Publishing House, Ltd; 1993: 40-44.

  26. Langevin E, Bairoch A, Appel RD, Rialle V, Scherrer JR, Hochstrasser DF. ExPASy: Un système expert pour l'analyse de séquences protéiques. 4èmes Journées Francophones d'Informatique Médicale. Bruxelles: June 1993.

  27. Vargas JR, Bologna G, Appel RD, Pellegrini C. Protein Maps Classification Using Neural Networks. Swiss Vision'93. Zurich: Sept. 1993.

  28. Vargas JR, Appel RD, Hochstrasser DF, Pellegrini C. Modeling and Quantification of Protein Maps by Gaussian Fitting. Proc. CAIP'93, 5th International Conference on Computer Analysis of Images and Patterns, Budapest, September 13-15, 1993. Springer Verlag; 1993: 627-633.

  29. Vargas JR, Bologna G, Appel RD, Hochstrasser DF, Pellegrini C. Classification of Protein Patterns using Neural Networks: Pixel based versus Feature based Approach. Proc. AIME'93, 5th Conference on AI in Medicine. Munich, Germany: Oct. 1993.

  30. Hochstrasser DF, Appel RD, Bairoch A, Golaz O, Pasquali C, Sanchez JC. Expert Protein Analysis Server (ExPASy). IMIA WG6 Working Conference. Vevey: May 1994.

  31. Friha L, Baujard O, Berry P, Appel RD. DISA: an interactive scheduler using abstractions. 14th Workshop of the UK Planning and Scheduling SIG, University of Essex. Colchester, U.K.: Nov. 1995.

  32. Mascarini C, Ratib O, Trayser G, Ligier Y, Appel RD. In-house Access to PACS Images and Related Data Through World Wide Web. SPIE International Symposium - Medical Imaging. Newport Beach, CA: Feb. 1996.

  33. Ratib O, Mascarini C, Trayser G, Revillard C, Ligier Y, Appel RD. The “INTRANET” concept applied for convenient access to PACS image data and computerized patient record. 14TH International EuroPACS Meeting. Heraklion, Crete, Hellas: Oct. 1996.

V. Abstracts and posters

  1. Hochstrasser D, Funk M, Appel R, Pellegrini C, Muller AF. Electrophorèses bidimensionnelles : analyse et comparaison automatique par ordinateur. Société Suisse de chimie clinique. Zürich: 1985.

  2. Hochstrasser D, Siegenthaler G, De Moerloose P, Funk M, Appel R, Pellegrini C, Saurat JH, Muller AF. Elévation de la protéine sérique liant le rétinol et de l'antithrombine III. Société Suisse de Médecine Interne. 1987.

  3. Hochstrasser D, Maignan MF, Dumont JM, Funk M, Appel R, Aellig A, Grandjean EM, Pellegrini C, Muller AF. 2-dimensional gel electrophoresis : a new tool for the evaluation of a therapeutic agent. 18th Congress of the International Union of Therapeutics. Geneva: Apr. 1987.

  4. Appel RD, Hochstrasser DF, Funk M, Roch C, Pun T, Pellegrini C. Automatic classification of 2 dimensional gel electrophoresis pictures by heuristic clustering. Electrophoresis '88. Copenhagen, Denmark: 1988.

  5. Funk M, Appel RD, Bost JM, Hochstrasser DF, Muller AF, Pellegrini C. A graphical Interface for the knowledge acquisition in the MELANIE expert system. Two-dimensional Electrophoresis. Vienna, Austria: Nov. 1988.

  6. Hochstrasser DF, Hochstrasser AC, Villars V, Funk M, Appel RD, Pellegrini C, Muller AF. Storable precast IEF gels with urea. Two-dimensional Electrophoresis. Vienna, Austria: Nov. 1988.

  7. Jaconi MEE, Theler JM, Schlegel W, Appel RD, Wright SD, Lew PD. Fluctuations of cytosolic free Ca2+ in human neutrophils: initiation by adherence receptors of the integrin family. American Society for Cell Biology. 1990.

  8. Ratib O, Appel RD, Scherrer JR. Papyrus : A Multimodality Image File Format for PACS and Teleradiology. Radiology. Nov. 1990: 320.

  9. Appel RD, Hochstrasser DF, Vargas R, Funk M, Pellegrini C, Muller AF, Scherrer JR. New Developments Toward Automatic Medical Diagnosis in the MELANIE Project. International Meeting of the Electrophoresis Societies. Washington DC: Mar. 1991.

  10. Burke P, Appel RD, Funk M, Hochstrasser DF, Scherrer JR. Can AI Help The Physician ? SCAICO 1991. Biel: Oct. 1991.

  11. Hochstrasser DF, Appel RD, Wiederkehr F, Funk M, Vonderschmidt D, Scherrer JR, Muller AF. Electrophorèses Bidimensionnelles en Chimie Clinique. Schweizerische Medizinische Wochenschrift, 121: suppl. 38, 59ème Assemblée Générale de la Société Suisse de Médecine. Lugano: May 1991.

  12. Jaconi M, Theler JM, Schlegel W, Appel RD, Wright SD, Lew PD. Repetitive cytosolic free CA2+ elevations in human neutrophils are initiated by adherence receptors of the integrin family. European Society for Clinical Investigation. Pisa: Apr. 1991.

  13. Appel RD, Vargas JR, Bjellqvist B, Corre JY, Snydr-Michal J, Burke P, Hochstrasser DF. Improving quantitative and qualitative analysis of 2D-PAGE images. Annual Meeting of the Electrophoresis Society. Research Triangle Park, NC: June 1992.

  14. Appel RD, Bairoch A, Miu M, Sanchez JC, Golaz O, Hochstrasser DF. SWISS-2DPAGE: A 2D-PAGE Image Database. Annual Symposium of the American Electrophoresis Society. Charleston: Nov. 1993.

  15. Hochstrasser D, Bjellqvist B, Bairoch A, Sanchez JC, Appel R, Hughes GJ. From the genome to 2D-PAGE or predicting the position of a polypeptide on protein maps. ICES-ELPHO 93. Oslo: June 1993.

  16. Hochstrasser DF, Appel RD, Sanchez JC. Clinical Applications of 2D-PAGE. ATB'93. Milan: Nov. 1993.

  17. Hochstrasser DF, Appel RD, Golaz O, Pasquali C, Sanchez JC. De la cartographie protéique au génome. Réunion annuelle de la Société Française d'Electrophorèse. Chambéry: Dec. 1993.

  18. Appel RD, Bairoch A, Peitsch M, Hochstrasser DF. Browsing through Molecular Biology Data on Internet : the ExPASy World-Wide Web Server. ACM Workshop on Information Retrieval and Genomics. Bethesda, MD: May 1994.

  19. Appel RD, Bairoch A, Sanchez JC, Pasquali C, Golaz O, Hochstrasser DF. World-Wide Web and the ExPASy Server. Siena Meeting on 2D Electrophoresis. Siena: Sept. 1994: 50-51.

  20. Bologna G, Appel RD, Hochstrasser DF. Automatic Classification of 2-D PAGE Images. Siena Meeting on 2D Electrophoresis. Siena: Sept. 1994: 56-57.

  21. Golaz O, Hughes G, Frutiger S, Paquet N, Sanchez JC, Pasquali C, Bairoch A, Appel RD, Hochstrasser DF. Plasma and red blood cell 2-D PAGE databases. Siena Meeting on 2D Electrophoresis. Siena: Sept. 1994: 158.

  22. Golaz O, Gravel P, Walzer C, Sanchez JC, Pasquali C, Appel RD, Hochstrasser DF. Sugar detection at the picomole level using lectins and chemiluminescence. Siena Meeting on 2D Electrophoresis. Siena: Sept. 1994: 43.

  23. Pasquali C, Schaller D, Appel RD, Sanchez JC, Golaz O, Humpherey-Smith I, Wilkins M, Williams K, Hughes GJ, Frutiger S, Paquet N, Hochstrasser DF. Two-dimensional gel electrophoresis of escherichia coli homogenates: identification of proteins spots by amino acid composition. Siena Meeting on 2D Electrophoresis. Siena: Sept. 1994: 84.

  24. Sanchez JC, Hughes G, Frutiger S, Paquet N, Pasquali C, Golaz O, Bairoch A, Appel RD, Hochstrasser DF. Human liver 2-D PAGE database. Siena Meeting on 2D Electrophoresis. Siena: Sept. 1994: 156.

  25. Sanchez JC, Appel R, Schaller D, Belet M, Muslena N, Deshusses J, Hochstrasser D. Global yeast genome expression analysed by 2-D PAGE after TCTP homolog gene (YKL312) disruption. 26th Annual Meeting of USGEB 94. Berne: 1994: 10-19.

  26. Wilkins M, Gooley A, Williams K, Humpherey-Smith I, Cordwell S, Appel RD, Sanchez JC, Golaz O, Pasquali C, Hochstrasser DF. Towards the Protein Genome: Rapid Identification of 2D Spots by Amino Acid Analysis. Siena Meeting on 2D Electrophoresis. Siena: Sept. 1994: 35-36.

  27. Hochstrasser DF, Wilkins M, Appel R, Bairoch A, Sanchez JC, Williams K. From Genomes to “Proteomes”: EXPASY & SWISS-2DPAGE. The Protein Society First European Symposium. Davos, Switzerland: May 1995.

  28. Sanchez JC, Golaz O, Schaller D, Frutiger S, Hughes G, Appel RD, Bairoch A, Linder P, Hochstrasser DF. The yeast SWISS-2DPAGE database. Swiss Yeast Meeting. Geneva: Sept. 1995.

  29. Sanchez JC, Golaz O, Schaller D, Morch F, Frutiger S, Hughes G, Appel RD, Deshusses J, Hochstrasser DF. The yeast SWISS-2DPAGE database. XVII International Conference on Yeast Genetics and Molecular Biology. Lisboa, Portugal: June 1995.

  30. Appel RD, Sanchez JC, Bairoch A, Hochstrasser DF. Federation of two-dimensional electrophoresis databases and integration with interactive data analysis programs. BIOINFORMATICS<-->STRUCTURE (reprinted in Folding & Design, vol. 1, supplement, 1996, p. S2). Jerusalem, Israel: Nov. 1996.

  31. Appel RD, Sanchez JC, Golaz O, Hochstrasser DF. World Wide Federation of 2D gel data bases. 2nd Siena 2D electrophoresis meeting. Siena, Italy: Sept. 1996.

  32. Boyer C, Baujard O, Baujard V, Aurel S, Selby M, Appel RD. HON automated database of health and medical information. MEDNET96 - European Congress on the Internet in Medicine. Brighton, U.K.: Oct. 1996.

  33. Golaz O, Sanchez JC, Heenan R, Ravier F, Rouge V, Tonella L, Wilkins MR, Appel RD, Hochstrasser DF. SWISS-2DISEASE: a 2-D database of samples in disease states. 2nd Siena 2D electrophoresis meeting. Siena, Italy: Sept. 1996.

  34. Mascarini C, Ratib O, Trayser G, Ligier Y, Appel RD. In-house access to PACS images and related data through World Wide Web. SGMR, 83. Jahresversammlung. Lausanne: May 1996.

  35. Peitsch MC, Tonella L, Sanchez JC, Wilkins MR, Appel RD, Hochstrasser DF. Automated comparative protein modelling and its integration with the SWISS-2DPAGE database. 2nd Siena 2D electrophoresis meeting. Siena, Italy: Sept. 1996.

  36. Ratib O, Mascarini C, Ligier Y, Appel RD, Trayser G. The World Wide Web for Intra- and Extra-Hospital Communication of Images and Patient Records. 3rd INCIS Workshop. Mainz: Apr. 1996.

  37. Selby M, Boyer C, Jenefski DA, Appel RD. Health On the Net Foundation Code of Conduct for Medical and Health Websites. MEDNET96 - European Congress on the Internet in Medicine. Brighton, U.K.: Oct. 1996.

  38. Wilkins MR, Gasteiger E, Sanchez JC, Appel RD, Hochstrasser DF. Protein identification with sequence tags. Curr Biol 1996; 6: 1543-1544.

  39. Wilkins MR, Sanchez JC, Ravier F, Tonella L, Appel RD, Hochstrasser DF. Vector maps in two-dimensional polyacrylamide gel electrophoresis - a means of predicting protein post-translational modification. 2nd Siena 2D electrophoresis meeting. Siena, Italy: Sept. 1996.

  40. Wilkins MR, Lindskog I, Ou K, Wheeler C, Sanchez JC, Yan J, Cartier P, Farnsworth V, Frutiger S, Hughes G, Ravier F, Tonella L, Gooley AA, Appel RD, Dunn MJ, Williams KL, Hochstrasser DF. Rapid protein identification for proteome projects. 2nd Siena 2D electrophoresis meeting. Siena, Italy: Sept. 1996.

  41. Baujard O, Baujard V, Aurel S, Boyer C, Appel RD. MARVIN - A multi-agent softbot to retrieve multilingual medical information on the Internet. MEDNET97 - European Congress on the Internet in Medicine. Brighton, U.K.: Nov. 1997.

  42. Boyer C, Selby M, Baujard V, Appel RD. Medical Information on the Internet: Who wants what? MEDNET97 - European Congress on the Internet in Medicine. Brighton, U.K.: Nov. 1997.

  43. Boyer C, Selby M, Appel RD. The Health On the Net Code of Conduct for medical and health Web sites; its status in 1997. MEDNET97 - European Congress on the Internet in Medicine. Brighton, U.K.: Nov. 1997.

  44. Hochstrasser D, Wilkins M, Sanchez JC, Gasteiger E, Appel R. Proteome Research: State of the art. Electrophorese Forum '97. Strasbourg: Nov. 1997.

  45. Tonella L, Ou K, Wilkins M, Sanchez JC, Frutiger S, Appel R, Bairoch A, Walsh BJ, Yan JX, Tyler M, Hoogland C, Rouge V, Morsch FS, Gooley AA, Hughes GJ, Williams KL, Hochstrasser DF. '97 Escherichia coli SWISS-2DPAGE database update. Electrophorese Forum '97. Strasbourg: Nov. 1997.

  46. Wilkins MR, Gasteiger E, Bairoch A, Sanchez JC, Hochstrasser DF, Appel RD. Software tools for mass spectrometric data analysis of proteins separated by 2-D gel electrophoresis. ICES’97. Seattle, Washington: Mar. 1997.

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