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NiceZyme View of ENZYME: EC 1.3.1.48

Official Name
15-oxoprostaglandin 13-oxidase.
Alternative Name(s)
15-oxo-Delta(13)-prostaglandin reductase.
Prostaglandin 13-reductase.
Reaction catalysed
11-alpha-hydroxy-9,15-dioxoprost-5-enoate + NAD(P)(+) <=> (5Z)-(13E)-11-alpha-hydroxy-9,15-dioxoprosta-5,13-dienoate + NAD(P)H
Comment(s)
  • Reduces 15-oxoprostaglandins to 13,14-dihydro derivatives.
  • The enzyme from placenta is specific for NAD(+).
Cross-references
BRENDA1.3.1.48
PUMA21.3.1.48
PRIAM enzyme-specific profiles1.3.1.48
KEGG Ligand Database for Enzyme Nomenclature1.3.1.48
IUBMB Enzyme Nomenclature1.3.1.48
IntEnz1.3.1.48
MEDLINEFind literature relating to 1.3.1.48
MetaCyc1.3.1.48

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