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NiceZyme View of ENZYME: EC 1.14.11.6

Official Name
Thymine dioxygenase.
Alternative Name(s)
Thymine 7-hydroxylase.
Thymine,2-oxoglutarate dioxygenase.
Reaction catalysed
Thymine + 2-oxoglutarate + O(2) <=> 5-hydroxymethyluracil + succinate + CO(2)
Cofactor(s)
Iron; L-ascorbic acid.
Comment(s)
Also acts on 5-hydroxymethyluracil to oxidize its -CH(2)-OH group first to -CHO and then to -COOH.
Cross-references
BRENDA1.14.11.6
PUMA21.14.11.6
PRIAM enzyme-specific profiles1.14.11.6
KEGG Ligand Database for Enzyme Nomenclature1.14.11.6
IUBMB Enzyme Nomenclature1.14.11.6
IntEnz1.14.11.6
MEDLINEFind literature relating to 1.14.11.6
MetaCyc1.14.11.6

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